Qiqi Feng¹, Zhijian Huang², Yanqiu Wang¹, Bin Wang^1,*

International Journal of Mental Health Promotion, Vol.26, No.6, pp. 417-428, 2024, DOI:10.32604/ijmhp.2024.049010 - 28 June 2024

Abstract Mindfulness-based interventions (MBIs) are emerging non-pharmacological treatments for mild traumatic brain injury (mTBI). In this systematic review, the authors aimed to evaluate the potential efficacy of MBIs to provide recommendations for treating patients with mTBI. We searched of the English literature on MBIs for patients with mTBI as of 01 September, 2023, using the PubMed, Web of Science, PsycINFO, and Scopus databases. One author performed data extraction and quality scoring of the included literature according to the proposed protocol, and another conducted the review. The review was not registered. A total of 11 studies met… More >

PING YANG^1,2,3, YUANXIANG LAN^1,2, ZHONG ZENG^1,2, YAN WANG^1,2, HECHUN XIA^1,2,*

BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367 - 30 January 2024

Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9… More > Graphic Abstract

LUOJUN ZHENG, LUAN WENG, DIWEN SHOU^*

BIOCELL, Vol.47, No.6, pp. 1345-1352, 2023, DOI:10.32604/biocell.2023.028866 - 19 May 2023

Abstract Background: Ischemic stroke is characterized by permanent or transient obstruction of blood flow, leading to a growing risk factor and health burden. Tianmagouteng yin (TMG) is commonly used in Chinese medicine to treat cerebral ischemia. The aim of this study was to investigate the neuroprotective effects of TMG against ischemic stroke. Methods: Either permanent middle cerebral artery occlusion (pMCAO) or sham operation was performed on anesthetized Wistar male rats (n = 36). Results: Results demonstrated that TMG administration reduced the infarction volume and mitigated the neurobehavioral deficits. Hematoxylin and eosin (HE) staining and Prussian blue staining revealed More >

Bin Yang^1,2,3,*, Hao Sun¹, Aiyuan Wang¹, Qun Wang²

Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 49-62, 2020, DOI:10.32604/mcb.2019.07534

Abstract In order to predict and evaluate injury mechanism and biomechanical response of the facial impact on head injury in a crash accident. With the combined modern medical imaging technologies, namely computed tomography (CT) and magnetic resonance imaging (MRI), both geometric and finite element (FE) models for human head-neck with detailed cranio-facial structure were developed. The cadaveric head impact tests were conducted to validate the headneck finite element model. The intracranial pressure, skull dynamic response and skull-brain relative displacement of the whole head-neck model were compared with experimental data. Nine typical cases of facial traffic accidents More >

Nesrine EBRAHIM¹, Eman EHSAN², Eman Abd EL GHANY², Dina SABRY³, Ashraf SHAMAA⁴

BIOCELL, Vol.43, No.1, pp. 21-28, 2019, DOI:10.32604/biocell.2019.06111

Abstract The neonatal hypoxic–ischemic encephalopathy (HIE) is an important cause of neurological morbidity and mortality in neonates. Cell therapy is considered a promising method for treating severe neurological disorders such as this one. Stem cells have the capacity for self-renewal and differentiation into certain cell lineages. The present study was aimed to find out the most beneficial route of bone marrow-derived mesenchymal stem cells (BMSCs) administration for the attenuation of experimentally induced HIE in neonatal rats. Sixty neonatal rats were divided randomly into four groups. Group 1: control group. Group 2: rats were exposed to… More >