SOROUSH SOLEYMANI¹, MOHAMMAD DOROUDIAN^2,*, MAHDIEH SOEZI^3,4, ALI BELADI⁵, KIARASH ASGARI², ASO MOBARAKSHAHI², ARYANA AGHAEIPOUR², RONAN MACLOUGHLIN^6,7,8,*

Oncology Research, Vol.33, No.1, pp. 15-26, 2025, DOI:10.32604/or.2024.053069 - 20 December 2024

Abstract Brain metastasis and primary glioblastoma multiforme represent the most common and lethal malignant brain tumors. Its median survival time is typically less than a year after diagnosis. One of the major challenges in treating these cancers is the efficiency of the transport of drugs to the central nervous system. The blood-brain barrier is cooperating with advanced stages of malignancy. The blood-brain barrier poses a significant challenge to delivering systemic medications to brain tumors. Nanodrug delivery systems have emerged as promising tools for effectively crossing this barrier. Additionally, the development of smart nanoparticles brings new hope More >

Mahesh Thyluru Ramakrishna¹, Kuppusamy Pothanaicker², Padma Selvaraj³, Surbhi Bhatia Khan^4,7,*, Vinoth Kumar Venkatesan⁵, Saeed Alzahrani⁶, Mohammad Alojail⁶

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 867-883, 2024, DOI:10.32604/cmc.2024.053563 - 15 October 2024

Abstract Brain tumor is a global issue due to which several people suffer, and its early diagnosis can help in the treatment in a more efficient manner. Identifying different types of brain tumors, including gliomas, meningiomas, pituitary tumors, as well as confirming the absence of tumors, poses a significant challenge using MRI images. Current approaches predominantly rely on traditional machine learning and basic deep learning methods for image classification. These methods often rely on manual feature extraction and basic convolutional neural networks (CNNs). The limitations include inadequate accuracy, poor generalization of new data, and limited ability… More >

JONG HWAN SUNG^*

BIOCELL, Vol.48, No.8, pp. 1145-1153, 2024, DOI:10.32604/biocell.2024.050365 - 02 August 2024

Abstract The gut is a digestive organ that absorbs nutrients but also plays a vital role in immune response and defense against external compounds. The complex interaction between the gut microbiota and other organs including the immune system of the host has been known in various contexts, yielding the notion of ‘axes’ between the gut and other organs. While the presence of various gut-organ axes has been reported, the lack of adequate in vitro model systems for studying this interaction has restricted a deeper insight into these phenomena. Recently developed microphysiological systems (MPS), also known as organ-on-a-chip, More >

Md. Atiqur Rahman¹, Mustavi Ibne Masum¹, Khan Md Hasib², M. F. Mridha^3,*, Sultan Alfarhood⁴, Mejdl Safran^4,*, Dunren Che⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2425-2448, 2024, DOI:10.32604/cmes.2024.050760 - 08 July 2024

Abstract Brain tumors pose a significant threat to human lives and have gained increasing attention as the tenth leading cause of global mortality. This study addresses the pressing issue of brain tumor classification using Magnetic resonance imaging (MRI). It focuses on distinguishing between Low-Grade Gliomas (LGG) and High-Grade Gliomas (HGG). LGGs are benign and typically manageable with surgical resection, while HGGs are malignant and more aggressive. The research introduces an innovative custom convolutional neural network (CNN) model, Glioma-CNN. GliomaCNN stands out as a lightweight CNN model compared to its predecessors. The research utilized the BraTS 2020 More >

Qiqi Feng¹, Zhijian Huang², Yanqiu Wang¹, Bin Wang^1,*

International Journal of Mental Health Promotion, Vol.26, No.6, pp. 417-428, 2024, DOI:10.32604/ijmhp.2024.049010 - 28 June 2024

Abstract Mindfulness-based interventions (MBIs) are emerging non-pharmacological treatments for mild traumatic brain injury (mTBI). In this systematic review, the authors aimed to evaluate the potential efficacy of MBIs to provide recommendations for treating patients with mTBI. We searched of the English literature on MBIs for patients with mTBI as of 01 September, 2023, using the PubMed, Web of Science, PsycINFO, and Scopus databases. One author performed data extraction and quality scoring of the included literature according to the proposed protocol, and another conducted the review. The review was not registered. A total of 11 studies met… More >

Yuting Zhou¹, Xuemei Yang¹, Junping Yin^2,3,4,*, Shiqi Liu¹

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5313-5333, 2024, DOI:10.32604/cmc.2024.052060 - 20 June 2024

Abstract Gliomas have the highest mortality rate of all brain tumors. Correctly classifying the glioma risk period can help doctors make reasonable treatment plans and improve patients’ survival rates. This paper proposes a hierarchical multi-scale attention feature fusion medical image classification network (HMAC-Net), which effectively combines global features and local features. The network framework consists of three parallel layers: The global feature extraction layer, the local feature extraction layer, and the multi-scale feature fusion layer. A linear sparse attention mechanism is designed in the global feature extraction layer to reduce information redundancy. In the local feature… More >

Zhenyu Qian¹, Yizhang Jiang¹, Zhou Hong¹, Lijun Huang², Fengda Li³, KhinWee Lai⁶, Kaijian Xia^4,5,6,*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4741-4762, 2024, DOI:10.32604/cmc.2024.050920 - 20 June 2024

Abstract In this paper, we introduce a novel Multi-scale and Auto-tuned Semi-supervised Deep Subspace Clustering (MAS-DSC) algorithm, aimed at addressing the challenges of deep subspace clustering in high-dimensional real-world data, particularly in the field of medical imaging. Traditional deep subspace clustering algorithms, which are mostly unsupervised, are limited in their ability to effectively utilize the inherent prior knowledge in medical images. Our MAS-DSC algorithm incorporates a semi-supervised learning framework that uses a small amount of labeled data to guide the clustering process, thereby enhancing the discriminative power of the feature representations. Additionally, the multi-scale feature extraction… More > Graphic Abstract

Samar M. Alqhtani¹, Toufique A. Soomro^2,*, Faisal Bin Ubaid³, Ahmed Ali⁴, Muhammad Irfan⁵, Abdullah A. Asiri⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1539-1562, 2024, DOI:10.32604/cmes.2024.051475 - 20 May 2024

Abstract Cancer-related to the nervous system and brain tumors is a leading cause of mortality in various countries. Magnetic resonance imaging (MRI) and computed tomography (CT) are utilized to capture brain images. MRI plays a crucial role in the diagnosis of brain tumors and the examination of other brain disorders. Typically, manual assessment of MRI images by radiologists or experts is performed to identify brain tumors and abnormalities in the early stages for timely intervention. However, early diagnosis of brain tumors is intricate, necessitating the use of computerized methods. This research introduces an innovative approach for… More > Graphic Abstract

Ahmed A. Alsheikhy¹, Ahmad S. Azzahrani¹, A. Khuzaim Alzahrani², Tawfeeq Shawly³

Computer Systems Science and Engineering, Vol.48, No.3, pp. 853-853, 2024, DOI:10.32604/csse.2024.051630 - 20 May 2024

Abstract This article has no abstract. More >

Fadl Dahan^*

Intelligent Automation & Soft Computing, Vol.39, No.2, pp. 381-395, 2024, DOI:10.32604/iasc.2024.047921 - 21 May 2024

Abstract In the domain of medical imaging, the accurate detection and classification of brain tumors is very important. This study introduces an advanced method for identifying camouflaged brain tumors within images. Our proposed model consists of three steps: Feature extraction, feature fusion, and then classification. The core of this model revolves around a feature extraction framework that combines color-transformed images with deep learning techniques, using the ResNet50 Convolutional Neural Network (CNN) architecture. So the focus is to extract robust feature from MRI images, particularly emphasizing weighted average features extracted from the first convolutional layer renowned for… More >