RéMY GAUTHIER1,*, HéLèNE FOLLET2, ANA-MARIA TRUNFIO-SFARGHIU3, DELPHINE FARLAY2, NINA ATTIK4,5, SYLVAIN MEILLE1, JéRôME CHEVALIER1, DAVID MITTON6
BIOCELL, Vol.46, No.10, pp. 2209-2216, 2022, DOI:10.32604/biocell.2022.022290
- 13 June 2022
Abstract To develop durable bone healing strategies through improved control of bone repair, it is of critical importance to understand the mechanisms of bone mechanical integrity when in contact with biomaterials and implants. Bone mechanical integrity is defined here as the adaptation of structural properties of remodeled bone in regard to an applied mechanical loading. Accordingly, the authors present why future investigations in bone repair and regeneration should emphasize on the matrix surrounding the osteocytes. Osteocytes are mechanosensitive cells considered as the orchestrators of bone remodeling, which is the biological process involved in bone homeostasis. These… More >
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