WENBIN LUO1, YULING ZOU2, HONGXI WU3, ZHONGYI YANG1, ZHIPENG YOU2,*
BIOCELL, Vol.48, No.8, pp. 1275-1284, 2024, DOI:10.32604/biocell.2024.051045
Abstract Background: Diabetes retinopathy (DR) is a complication of diabetes that affects patients’ vision. Previous studies have found blueberry anthocyanins extract (BAE) can inhibit the progression of DR, but its mechanism is not completely clear. Methods: To study the role of BAE in diabetes retinopathy, we treated human retinal endothelial cells (HRCECs) with 30 mM high glucose to simulate the microenvironment of diabetes retinopathy and used BAE to intervene the in vitro high glucose-induced retinopathy model. HRCEC cell viability and apoptosis rates were examined by Cell Counting Kit 8 (CCK-8) assay and flow cytometry assay. The binding… More >
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