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  • Open Access

    ARTICLE

    Optimal Bioprinting Parameters and Experimental Investigation of Acellular Dermal Matrix Scaffold

    Qingxi Hu1,2,3, Yiming Wang1, Dongchao Yang4, Haiguang Zhang1,2,3,*, Zhicheng Song4, Yan Gu4,*

    Journal of Renewable Materials, Vol.9, No.1, pp. 1-16, 2021, DOI:10.32604/jrm.2021.013319

    Abstract Acellular dermal matrix (ADM) as a biomaterial is currently believed to be promising tissue repair improvement. With the development of tissue engineering, ADM is increasingly used as biological scaffolds. We explored the feasibility and performance of ADM biological scaffolds that fabricated by 3D printing. This paper presented our study on the printability of 3D printed ADM scaffolds, with a focus on identifying the influence of printing parameters/conditions on printability. To characterize the printability, we examined the fiber morphology, pore size, strand diameter, and mechanical property of the printed scaffolds. Our results revealed that the printability could be affected by a… More >

  • Open Access

    ARTICLE

    Optimization and comparison of two different 3D culture methods to prepare cell aggregates as a bioink for organ printing

    RANA IMANI1, SHAHRIAR HOJJATI EMAMI1, HOSSEIN FAKHRZADEH2, NAFISEH BAHEIRAEI1, ALI M SHARIFI* 2,3,4

    BIOCELL, Vol.36, No.1, pp. 37-45, 2012, DOI:10.32604/biocell.2012.36.037

    Abstract The ultimate goal of tissue engineering is to design and fabricate functional human tissues that are similar to natural cells and are capable of regeneration. Preparation of cell aggregates is one of the important steps in 3D tissue engineering technology, particularly in organ printing. Two simple methods, hanging drop (HD) and conical tube (CT) were utilized to prepare cell aggregates. The size and viability of the aggregates obtained at different initial cell densities and pre-culture duration were compared. The proliferative ability of the cell aggregates and their ability to spread in culture plates were also investigated. In both methods, the… More >

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