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  • Open Access

    ARTICLE

    MAPK9 as a therapeutic target: unveiling ferroptosis in localized prostate cancer progression

    CHENG-GONG LUO1,2,#, JIAO ZHANG1,#, YUN-ZHAO AN1, XUAN LIU1, SHUAI-JIE LI1, WEI ZHANG1, KAI LI1, XU ZHAO1, DONG-BO YUAN1, LING-YUE AN1, WEI CHEN2, YE TIAN1,*, BIN XU1,*

    BIOCELL, Vol.48, No.5, pp. 771-792, 2024, DOI:10.32604/biocell.2024.048878

    Abstract Background: Ferroptosis, a lipid peroxidation-mediated programmed cell death, is closely linked to tumor development, including prostate cancer (PCa). Despite established connections between ferroptosis and PCa, a comprehensive investigation is essential for understanding its impact on patient prognosis. Methods: A risk model incorporating four ferroptosis-related genes was developed and validated. Elevated risk scores correlated with an increased likelihood of biochemical recurrence (BCR), diminished immune infiltration, and adverse clinicopathological characteristics. To corroborate these results, we performed validation analyses utilizing datasets from both the Cancer Genome Atlas Cohort (TCGA) and the Gene Expression Synthesis Cohort (GEO). Moreover, we conducted… More >

  • Open Access

    ARTICLE

    Physiological and Biochemical Mechanisms of Salinity Tolerance in Carex morrowii Boott

    Aysegul Akpinar*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 2197-2210, 2023, DOI:10.32604/phyton.2023.029006

    Abstract Carex species are widely used in many parts of the world and contain a large number of ecologically diverse species. Among the Carex species, some of them are known to be glycophytes, while others are halophytes. Carex morrowii Boott (Cyperaceae) is resistant to trample through their root structure and has an essential ornamental value in the landscape with their leaves. However, no information was found about the level of salinity tolerance/ sensitivity of the Carex morrowii among these species. In the present study, changes in trace element contents (Na, K, Ca, Cu, Mn, Mg, Ni, Fe, P,… More >

  • Open Access

    REVIEW

    Biofuel Recovery from Plantain and Banana Plant Wastes: Integration of Biochemical and Thermochemical Approach

    Abdulmoseen Segun Giwa1,*, Mingqiang Sheng2, Ndungutse Jean Maurice3, Xinxin Liu1, Zelong Wang1, Fengmin Chang4, Bo Huang4, Kaijun Wang4

    Journal of Renewable Materials, Vol.11, No.6, pp. 2593-2629, 2023, DOI:10.32604/jrm.2023.026314

    Abstract Globally, fossil fuel dependence has created several environmental challenges and climate change. Hence, creating other alternative renewable and ecologically friendly bio-energy sources is necessary. Lignocellulosic biomass has gained significant attention recently as a renewable material for biofuel production. The large amounts of plantain and banana plant parts wasted after harvesting, as well as the peels generated daily by the fruit market and industries, demonstrate the potential of bioenergy resources. This review briefly assesses plantain and banana plant biomass (PBB) generated in the developing, developed, and underdeveloped countries, the consumable parts, and feasible products yield. It… More > Graphic Abstract

    Biofuel Recovery from Plantain and Banana Plant Wastes: Integration of Biochemical and Thermochemical Approach

  • Open Access

    REVIEW

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

    Kakudji Kisimba1, Anand Krishnan2,*, Mbuso Faya1, Kahumba Byanga3, Kabange Kasumbwe4, Kaliyapillai Vijayakumar5, Ram Prasad6,*

    Journal of Renewable Materials, Vol.11, No.6, pp. 2575-2591, 2023, DOI:10.32604/jrm.2023.026159

    Abstract Nanoparticles have distinct properties that make them potentially valuable in a variety of industries. As a result, emerging approaches for the manufacture of nanoparticles are gaining a lot of scientific interest. The biological pathway of nanoparticle synthesis has been suggested as an effective, affordable, and environmentally safe method. Synthesis of nanoparticles through physical and chemical processes uses unsafe materials, expensive equipment and adversely affects the environment. As a result, in order to support the increased utilization of nanoparticles across many sectors, nanotechnology research activities have shifted toward environmentally safe and cost-effective techniques that outperform chemical… More > Graphic Abstract

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

  • Open Access

    REVIEW

    Biochemical Mechanism Unlocking Their Potential Role in Salt Tolerance Mechanism of Zizyphus Germplasm

    Riaz Ahmad1,*, Hafiza Muniba Din Muhammad2, Safina Naz2, Meryam Manzoor2, Muhammad Ahsan Altaf3

    Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1539-1553, 2023, DOI:10.32604/phyton.2023.026672

    Abstract Salinity is one of the major constraints reducing plant growth and yield. Irrigation with poor quality and brackish water to orchards is a major cause of stunted growth and low yield. The salt tolerance mechanism is one of the complicated genomic characters that is very problematic to develop in fruit trees and becomes much more severe at any growth and developmental stage. Osmotic stress and hormonal imbalances are major constraints causing low biomass production. Fruit tree tolerance/sensitivity is chiefly based on the activation of a defense system comprised of super-oxidase dismutase (SOD), peroxidase (POD) and… More >

  • Open Access

    REVIEW

    The Genetic and Biochemical Mechanisms Underlying Cereal Seed Dormancy

    Sasa Jing1, Yuan Tian1, Heng Zhang2, John T. Hancock3, Ying Zhu2,*, Ping Li1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.4, pp. 1203-1214, 2023, DOI:10.32604/phyton.2023.026305

    Abstract The crop seeds have been a staple food for humans, and seed yield is important for sustaining agriculture development and enhancing human adaptability to food risks. The phenomenon of pre-harvest sprouting (PHS), caused by seed dormancy deficiency, and the phenomenon of low seedling emergence caused by seed deep dormancy, will lead to a reduction in agricultural production. Therefore, it is particularly important to understand the regulation mechanisms of seed dormancy. There are many studies on the regulation of seed dormancy in rice, but there are few studies on the regulation of seed dormancy in other More >

  • Open Access

    ARTICLE

    Improvement of Selected Morphological, Physiological, and Biochemical Parameters of Banana (Musa acuminata L.) Using Potassium Silicate under Drought Stress Condition Grown in vitro

    Hosny Abdel Aziz1, Mohamed Sharaf2,3, Magdy Omar4, Ahmed Abou El-Yazied5, Nada Ibrahim AlJwaizea6, Shaimaa Ismail5, Mohamed M. A. Omar7, Khadiga Alharbi6,*, Amr Elkelish8,9, Moataz Tawfik10

    Phyton-International Journal of Experimental Botany, Vol.92, No.4, pp. 1019-1036, 2023, DOI:10.32604/phyton.2023.026769

    Abstract Drought stress has become more common in recent years as a result of climate change impacts on the production of banana crops and other fruit trees. The growth and productivity of Musa spp are severely impacted by the gradual degradation of water resources and the erratic distribution pattern of annual precipitation amount. The aim of the work includes increased drought tolerance in light of water scarcity in the world as a result of the bananas’ being gluttonous for water needs. This investigation was carried out from 2019 to 2020 to study the effect of potassium silicate… More >

  • Open Access

    REVIEW

    Biochemical association between the prevalence of genetic polymorphism and myocardial infarction

    MOMINA SHAHID1, KANWAL REHMAN2, MUHAMMAD SAJID HAMID AKASH1,*, SHALEEM SUHAIL1, SUMBAL RASHEED1, MUHAMMAD IMRAN3,4, MOHAMMED A. ASSIRI3,4

    BIOCELL, Vol.47, No.3, pp. 473-484, 2023, DOI:10.32604/biocell.2023.025930

    Abstract Genetic polymorphism has a vital role in the pathogenesis and development of myocardial infarction (MI). Single nucleotide polymorphism at any one of the amino acid sequences can result in a diseased state. A single gene can exhibit genetic polymorphism at more than one position giving rise to different variants. Genetic polymorphism of angiotensinogen (AGT) M235T, AGT T174M, and angiotensin-1-converting enzyme (ACE) I/D, endothelial nitric oxide synthase (eNOS), and methylenetetrahydrofolate reductase (MTHFR) can be a risk factor for MI. However, it is important to study the prevalence of genetic polymorphisms of these genes among different populations. More >

  • Open Access

    ARTICLE

    Biochemical and Physiological Responses of Arabidopsis thaliana Leaves to Moderate Mechanical Stimulation

    Iva Šutevski1,#, Klara Krmpotić1,#, Sandra Vitko1, Nataša Bauer1, Eva Fancev2, Mario Cifrek2, Željka Vidaković-Cifrek1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 901-920, 2023, DOI:10.32604/phyton.2023.025165

    Abstract Mechanical stimulation of plants can be caused by various abiotic and biotic environmental factors. Apart from the negative consequences, it can also cause positive changes, such as acclimatization of plants to stress conditions. Therefore, it is necessary to study the physiological and biochemical mechanisms underlying the response of plants to mechanical stimulation. Our aim was to evaluate the response of model plant Arabidopsis thaliana to a moderate force of 5 N (newton) for 20 s, which could be compared with the pressure caused by animal movement and weather conditions such as heavy rain. Mechanically stimulated leaves… More >

  • Open Access

    ARTICLE

    Physiological and Biochemical Characteristics and Response Patterns of Salinity Stress Responsive Genes (SSRGs) in Wild Quinoa (Chenopodium quinoa L.)

    Yurong Jiang1, Muhammad Yasir1, Yuefen Cao1, Lejia Hu1, Tongli Yan1, Shuijin Zhu2,*, Guoquan Lu1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 399-410, 2023, DOI:10.32604/phyton.2022.022742

    Abstract Cultivating salt-tolerant crops is a feasible way to effectively utilize saline-alkali land and solve the problem of underutilization of saline soils. Quinoa, a protein-comprehensive cereal in the plant kingdom, is an exceptional crop in terms of salt stress tolerance level. It seems an excellent model for the exploration of salt-tolerance mechanisms and cultivation of salt-tolerant germplasms. In this study, the seeds and seedlings of the quinoa cultivar Shelly were treated with different concentrations of NaCl solution. The physiological, biochemical characteristics and agronomic traits were investigated, and the response patterns of three salt stress-responsive genes (SSRGs)… More >

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