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  • Open Access

    ARTICLE

    Recognizing Breast Cancer Using Edge-Weighted Texture Features of Histopathology Images

    Arslan Akram1,2, Javed Rashid2,3,4, Fahima Hajjej5, Sobia Yaqoob1,6, Muhammad Hamid7, Asma Irshad8, Nadeem Sarwar9,*

    CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1081-1101, 2023, DOI:10.32604/cmc.2023.041558 - 31 October 2023

    Abstract Around one in eight women will be diagnosed with breast cancer at some time. Improved patient outcomes necessitate both early detection and an accurate diagnosis. Histological images are routinely utilized in the process of diagnosing breast cancer. Methods proposed in recent research only focus on classifying breast cancer on specific magnification levels. No study has focused on using a combined dataset with multiple magnification levels to classify breast cancer. A strategy for detecting breast cancer is provided in the context of this investigation. Histopathology image texture data is used with the wavelet transform in this… More >

  • Open Access

    ARTICLE

    Chemokine and chemokine receptor patterns in patients with benign and malignant salivary gland tumors: a distinct role for CCR7

    Mohammad Reza Haghshenas1, Mohammad Javad Ashraf2, Bijan Khademi3, Abbas Ghaderi1,4, Nasrollah Erfani1, Mahboobeh Razmkhah1

    European Cytokine Network, Vol.28, No.1, pp. 27-35, 2017, DOI:10.1684/ecn.2017.0388

    Abstract Background: To explore the molecular mechanisms involved in pathophysiology of malignant and benign salivary gland tumors (SGTs), we investigated main tumor-inducing chemokines and chemokine receptors, CXCL12/CXCR4/ACKR3 (CXCR7), CXCR3/CXCL10, CCR5/CCL5, CCL21/CCR7, CCL2, CCR4, CXCR5, CCR6, and CXCL8 in tumor tissues. Patients and methods: Parotid tissues were obtained from 30 patients with malignant and benign SGTs. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to determine the mRNA expression pattern of the mentioned chemokines/chemokine receptors and immunohistochemistry (IHC) was performed to verify the expression of CCR7. Results: Expression levels of CCR7 and CCR4 transcripts were higher in… More >

  • Open Access

    ARTICLE

    Adrenalectomy for benign and malignant disease: utilization and outcomes by surgeon specialty and surgical approach from 2003-2013

    Izak Faiena1, Alexandra Tabakin1, Jeffrey Leow2, Neal Patel1, Parth K. Modi1, Amirali H. Salmasi1, Benjamin I. Chung3, Steven L. Chang2, Eric A. Singer1

    Canadian Journal of Urology, Vol.24, No.5, pp. 8990-8997, 2017

    Abstract Introduction: Data on the utilization of open, laparoscopic and robotic adrenalectomy on a national level is limited.
    Materials and methods: Data on patients who underwent open, laparoscopic, or robotic adrenalectomy for benign or malignant disease in the US from 2003-2013 were extracted using ICD-9 codes from the Premier Hospital Database. Surgeon specialty, patient demographics, hospital characteristics, and complications were compared. Data were analyzed using univariate and multivariable logistic regression analyses.
    Results: A total of 8,831 adrenalectomies were performed for benign and malignant tumors. There was no significant difference in rate of adrenalectomy with regards to comorbidities, insurance status,… More >

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