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    ARTICLE

    Bendamustine and rituximab as frontline therapy in extranodal marginal zone lymphoma: a single-institution experience

    CONSTANTINE N. LOGOTHETIS1, NATHAN P. HORVAT2, TONY KURIAN3, CELESTE BELLO3, JULIO CHAVEZ3, LEIDY ISENALUMHE3, BIJAL SHAH3, LUBOMIR SOKOL3, HAYDER SAEED3, JAVIER PINILLA3, SAMEH GABALLA3,*

    Oncology Research, Vol.32, No.6, pp. 1031-1036, 2024, DOI:10.32604/or.2024.046885 - 23 May 2024

    Abstract Extranodal marginal zone lymphoma (EMZL) encompasses 70% of cases of marginal zone lymphoma. Frontline bendamustine and rituximab (BR) were derived from trials involving other indolent non-Hodgkin’s lymphomas. Only one trial has evaluated frontline BR prospectively in EMZL. This retrospective study reports outcomes among EMZL patients receiving frontline BR. Twenty-five patients were included with a median age of 69 years (40–81). Five (20.0%) patients had stage I/II disease, and 20 (80.0%) had stage III/IV disease. The median number of cycles was 6.0 (3.0–6.0). Maintenance rituximab was administered to 10 (41.7%) individuals. Overall response rate (ORR) was More >

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