MIN TANG^1,#, XUELING HE^1,2,#, XINGHONG YAO¹, JIRUI WEN¹, MINGYUE BAO¹, LIANG LI^1,*

BIOCELL, Vol.46, No.6, pp. 1465-1472, 2022, DOI:10.32604/biocell.2022.018967 - 07 February 2022

Abstract The present study was designed to investigate the role of estrogen receptor α (ERα) in biaxial tensile strain (BTS) regulated osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (rBMSCs). rBMSCs were derived from rats and overexpressed ERα. The rBMSCs were subjected to BTS at 1 Hz with a strain of 2% for 4 h per day, 3 days, with or without ERα inhibitor ICI 182,780 (ICI). Then, bone mineralization was performed by Alizarin Red Staining. The markers of osteogenic differentiation and downstream Wnt3a/β-catenin signaling were detected by western blotting. Results showed that BTS enhanced More >

Arif Mehmood¹, Muhammad Aslam², Muhammad Imran Khan³, Humera Qureshi³, Choonkil Park^4,*, Jung Rye Lee⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.3, pp. 1565-1585, 2022, DOI:10.32604/cmes.2022.018518 - 30 December 2021

Abstract In this article, new generalized neutrosophic soft * _b open set is introduced in neutrosophic soft bi-topological structurers (NSBTS) concerning soft points of the space. This new set is produced by making the marriage of soft semi-open set with soft pre-open set in neutrosophic soft topological structure. An ample of results are investigated in NSBTS on the basis of this new neutrosophic soft * _b open set. Proper examples are settled for justification of these results. The non-validity of some results is vindicated with examples. More >