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  • Open Access

    ARTICLE

    Deep Learning-Based Digital Image Forgery Detection Using Transfer Learning

    Emad Ul Haq Qazi1,*, Tanveer Zia1, Muhammad Imran2, Muhammad Hamza Faheem1

    Intelligent Automation & Soft Computing, Vol.38, No.3, pp. 225-240, 2023, DOI:10.32604/iasc.2023.041181

    Abstract Deep learning is considered one of the most efficient and reliable methods through which the legitimacy of a digital image can be verified. In the current cyber world where deepfakes have shaken the global community, confirming the legitimacy of a digital image is of great importance. With the advancements made in deep learning techniques, now we can efficiently train and develop state-of-the-art digital image forensic models. The most traditional and widely used method by researchers is convolution neural networks (CNN) for verification of image authenticity but it consumes a considerable number of resources and requires a large dataset for training.… More >

  • Open Access

    ARTICLE

    Bioinformatic analysis and in vivo validation of angiogenesis related genes in inflammatory bowel disease

    ZEPENG DONG, CHENYE ZHAO, SHIBO HU, KUI YANG, JUNHUI YU*, XUEJUN SUN, JIANBAO ZHENG*

    BIOCELL, Vol.47, No.12, pp. 2735-2745, 2023, DOI:10.32604/biocell.2023.043422

    Abstract Objectives: Angiogenesis plays a significant role in the occurrence and development of inflammatory bowel disease (IBD). The aim of this study is to explore potential angiogenesis related genes (ARGs) in IBD through bioinformatics analysis and in vivo experiments. Methods: GSE57945, GSE87466, and GSE36807 were obtained from the Gene Expression Omnibus database. GSE57945 was used as the training set, while GSE87466 and GSE36807 were used as the validation set. The key ARGs associated with IBD were identified using the least absolute shrinkage and selection operator (LASSO) and random forest methods. These identified ARGs were then utilized to construct a diagnostic model… More >

  • Open Access

    REVIEW

    Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms

    AMYLLY SANUELLY DA PAZ MARTINS1,#, MARLA DE CERQUEIRA ALVES2,#, ORLANDO ROBERTO PIMENTEL DE ARAÚJO3, FABIANA OLIVEIRA DOS SANTOS CAMATARI4, MARÍLIA OLIVEIRA FONSECA GOULART1,3,5, FABIANA ANDRÉA MOURA2,6,*

    BIOCELL, Vol.47, No.11, pp. 2547-2566, 2023, DOI:10.32604/biocell.2023.043253

    Abstract

    Curcumin, a natural product, has exhibited promising effects in both animal models and clinical trials, interacting with a multitude of factors linked to Inflammatory Bowel Disease (IBD). These factors encompass cytokines, oxidative stress-associated enzymes, and modulation of the intestinal microbiota. Notably, curcumin has demonstrated therapeutic potential in animal models of colitis, wherein it exerts a negative regulatory influence on pivotal signaling pathways such as PI3/Akt, JAK/STAT, and β-catenin. Moreover, it inhibits the expression of pro-inflammatory enzymes and co-stimulatory molecules (including RANKL, ICAM-1, CD205, CD256, TLR4, among others), while curbing immune cell chemotaxis, thereby attenuating the characteristic neutrophil infiltration observed in… More > Graphic Abstract

    Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms

  • Open Access

    ARTICLE

    K-Hyperparameter Tuning in High-Dimensional Space Clustering: Solving Smooth Elbow Challenges Using an Ensemble Based Technique of a Self-Adapting Autoencoder and Internal Validation Indexes

    Rufus Gikera1,*, Jonathan Mwaura2, Elizaphan Muuro3, Shadrack Mambo3

    Journal on Artificial Intelligence, Vol.5, pp. 75-112, 2023, DOI:10.32604/jai.2023.043229

    Abstract k-means is a popular clustering algorithm because of its simplicity and scalability to handle large datasets. However, one of its setbacks is the challenge of identifying the correct k-hyperparameter value. Tuning this value correctly is critical for building effective k-means models. The use of the traditional elbow method to help identify this value has a long-standing literature. However, when using this method with certain datasets, smooth curves may appear, making it challenging to identify the k-value due to its unclear nature. On the other hand, various internal validation indexes, which are proposed as a solution to this issue, may be… More >

  • Open Access

    ARTICLE

    Solar Radiation Prediction Using Satin Bowerbird Optimization with Modified Deep Learning

    Sheren Sadiq Hasan1, Zainab Salih Agee2, Bareen Shamsaldeen Tahir3, Subhi R. M. Zeebaree4,*

    Computer Systems Science and Engineering, Vol.46, No.3, pp. 3225-3238, 2023, DOI:10.32604/csse.2023.037434

    Abstract Solar energy will be a great alternative to fossil fuels since it is clean and renewable. The photovoltaic (PV) mechanism produces sunbeams’ green energy without noise or pollution. The PV mechanism seems simple, seldom malfunctioning, and easy to install. PV energy productivity significantly contributes to smart grids through many small PV mechanisms. Precise solar radiation (SR) prediction could substantially reduce the impact and cost relating to the advancement of solar energy. In recent times, several SR predictive mechanism was formulated, namely artificial neural network (ANN), autoregressive moving average, and support vector machine (SVM). Therefore, this article develops an optimal Modified… More >

  • Open Access

    ARTICLE

    Efficacy of Singing Bowls in Childhood Asthma—A Pilot and Feasibility Study

    Sukhbir Shahid*

    Sound & Vibration, Vol.56, No.3, pp. 245-253, 2022, DOI:10.32604/sv.2022.016139

    Abstract The potential use of sound and vibration for diagnostic and therapeutic purposes remains largely under-explored and under-estimated. Sound and vibrational energy has great positive impact on the mind and body. It could be particularly useful for psychosomatic diseases as a complementary therapy. Singing bowls, the spiritual ancient therapy has been claimed to aid in mind relaxation and painful and inflammatory conditions. Childhood asthma is an inflammatory airway disease and a psychosomatic disorder. The psychological management in it is often neglected leading to under-treatment or a relapse. Hence, we hypothesized that sound therapy with singing bowls might be useful as complementary… More >

  • Open Access

    ARTICLE

    Modified Satin Bowerbird for Distributed Generation in Remotely Controlled Voltage Bus

    K. Dharani Sree*, P. Karpagavalli

    Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 1181-1195, 2023, DOI:10.32604/iasc.2023.025303

    Abstract The distributed generators in the radial distribution network are to improve the Grid performance and its efficiency. These Distributed Generators control the PV bus; it is converted as a remote controlled PVQ bus. This PVQ bus reduces the power loss and reactive power. Initially, the distributed generators were placed in the system using mathematical modelling or the optimization. This approach improves the efficiency but it has no effect in loss minimization. To minimize the loss the reconfigured network with Genetic algorithm based Distributed generator placement proposed as existing work. This approach minimizes the loss effectively; but the genetic algorithm takes… More >

  • Open Access

    ARTICLE

    Prevalence and Factors Associated with Depression, Anxiety and Stress in IBD Patients Undergoing Intravenous Biological Therapy during the COVID-19 Pandemic-Montenegro Experience

    Brigita Smolović1,2, Marija Đurović1, Miloš Lukić1, Marija Abramović2,3, Damir Muhović1,2,*

    International Journal of Mental Health Promotion, Vol.24, No.4, pp. 551-564, 2022, DOI:10.32604/ijmhp.2022.020347

    Abstract Throughout its duration, the coronavirus disease 2019 (COVID-19) pandemic has been affecting lives worldwide and has had a sizeable impact on mental health, particularly for those who already suffer from a chronic illnesses. Depression, Anxiety and Stress (DAS) are common psychiatric comorbidities in inflammatory bowel disease (IBD) patients. This study aims to determine the prevalence and risk factors for moderate and severe symptoms of DAS in IBD patients have been undergoing intravenous biological therapy (IvBTh) during the COVID-19 pandemic. The study was conducted between September 1st and November 30th, 2020 at the Clinical Center of Montenegro-IBD unit, where all patients… More >

  • Open Access

    REVIEW

    Efficacy of oral consumption of curcumin/ for symptom improvement in inflammatory bowel disease: A systematic review of animal models and a meta-analysis of randomized clinical trials

    MARLA DE CERQUEIRA ALVES1, MONISE OLIVEIRA SANTOS1, NASSIB BEZERRA BUENO1, ORLANDO ROBERTO PIMENTEL DE ARAÚJO2, MARÍLIA OLIVEIRA FONSECA GOULART2,3,4, FABIANA ANDRÉA MOURA1,5,*

    BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407

    Abstract

    The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

  • Open Access

    ARTICLE

    Intelligent Satin Bowerbird Optimizer Based Compression Technique for Remote Sensing Images

    M. Saravanan1, J. Jayanthi2, U. Sakthi3, R. Rajkumar4, Gyanendra Prasad Joshi5, L. Minh Dang5, Hyeonjoon Moon5,*

    CMC-Computers, Materials & Continua, Vol.72, No.2, pp. 2683-2696, 2022, DOI:10.32604/cmc.2022.025642

    Abstract Due to latest advancements in the field of remote sensing, it becomes easier to acquire high quality images by the use of various satellites along with the sensing components. But the massive quantity of data poses a challenging issue to store and effectively transmit the remote sensing images. Therefore, image compression techniques can be utilized to process remote sensing images. In this aspect, vector quantization (VQ) can be employed for image compression and the widely applied VQ approach is Linde–Buzo–Gray (LBG) which creates a local optimum codebook for image construction. The process of constructing the codebook can be treated as… More >

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