Chel-Guerrero LD1, R Gómez-Cansino2, SL Gúzman-Gutierrez3, MG Campos-Lara4, E Saury-Duch1, F Díaz de León Sánchez5, R Reyes-Chilpa6, JA Mendoza-Espinoza7
Phyton-International Journal of Experimental Botany, Vol.87, pp. 68-71, 2018, DOI:10.32604/phyton.2018.87.068
Abstract The objective of this study was to investigate extracts
from the peels of Annona squamosa L. (purple sugar apple), Annona
reticulata L. (custard apple), Chrysophyllum cainito L. (green
star apple), and Melicoccus bijugatus Jacq. (mamoncillo), as potential
sources of anti-HIV-1 agents. Methanolic extracts from the peels
of the aforementioned tropical fruits were obtained by maceration.
Antiviral activity was evaluated through HIV-1 RT inhibition by
extracts, using a non-radioactive immuno/colorimetric assay (Lenti
RT Activity Assay, Cavidi Tech). Assay was performed according to
the protocol provided by the manufacturer. Extracts from the peels
of A. squamosa, A. reticulata, and C. cainito showed high More >
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