Virna Margarita Martín Giménez¹, SebastiáN GarcíA MenéNdez^2,3, Luiz Gustavo A. Chuffa⁴, Vinicius Augusto SimãO⁴, Russel J. Reiter⁵, Ramaswamy Sharma⁶, Walter Balduini⁷, Carla Gentile⁸, Walter Manucha^2,3,*

BIOCELL, Vol.49, No.12, pp. 2245-2282, 2025, DOI:10.32604/biocell.2025.071830 - 24 December 2025

Abstract Neurodegenerative diseases (NDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are characterized by progressive neuronal loss, which is closely linked to mitochondrial dysfunction. These pathologies involve a complex interplay of genetics, protein misfolding, and cellular stress, culminating in impaired energy metabolism, an increase in reactive oxygen species (ROS), and defective mitochondrial quality control. The accumulation of damaged mitochondria and dysregulation of pathways such as the Integrated Stress Response (ISR) are central to the pathogenesis of these conditions. This review explores the critical relationship between mitochondrial stress… More >

Nada Zaari Jabri¹, Mohamed Ait-El-Mokhtar^1,*, Fadoua Mekkaoui¹, Najwa Rabah¹, Ilham Amghar¹, Ghizlane Diria², Abdelaziz Hmyene¹

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3687-3701, 2025, DOI:10.32604/phyton.2025.071634 - 01 December 2025

Abstract Cadmium (Cd) contamination is a major environmental stressor that adversely affects crop germination and early development. This study assessed the impact of increasing Cd concentrations (0.125 to 1 g/L) on seed germination and early seedling growth in three bread wheat (Triticum aestivum L.) cultivars: Achtar, Lina, and Snina. The results revealed a clear dose-dependent inhibitory effect of Cd. Germination percentage (GP) significantly declined with increasing Cd levels, while mean germination time was progressively delayed, particularly at higher concentrations. Vigor index (VI) also showed significant reductions, reflecting compromised seedling establishment. Morphological traits, especially shoot and root lengths,… More >

Riya Tripathi, Varsha K. Singh, Palak Rana, Sapana Jha, Ashish P. Singh, Payel Rana, Rajeshwar P. Sinha^*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3371-3399, 2025, DOI:10.32604/phyton.2025.070712 - 01 December 2025

Abstract Cyanobacteria are photosynthetic prokaryotes. They exhibit remarkable metabolic adaptability, enabling them to withstand oxidative stress, high salinity, temperature extremes, and UV radiation (UVR). Their adaptive strategies involve complex regulatory networks that affect gene expression, enzyme activity, and metabolite fluxes to maintain cellular homeostasis. Key stress response systems include the production of antioxidants such as peroxidases (POD), catalase (CAT), and superoxide dismutase (SOD), which detoxify reactive oxygen species (ROS). To withstand environmental stresses, cyanobacteria maintain osmotic balance by accumulating compatible solutes, such as glycine betaine, sucrose, and trehalose. They also adapt to temperature and light fluctuations… More >

Xiaomei He¹, Xiaoting Wan¹, Muhammad Arif ², Ziyang Hu¹, Haiyu Wang¹, Muhammad Aamir Manzoor^3,*, Cheng Song^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 2985-3002, 2025, DOI:10.32604/phyton.2025.070697 - 29 October 2025

Abstract Melatonin is a multifunctional molecule found in all organisms that has been shown to play a crucial role in plant growth, development, and stress response. Plant melatonin is typically synthesized in organelles termed chloroplasts, and the mechanisms of its synthesis and metabolic pathways have been extensively studied. Melatonin serves a significant regulatory function in plant growth and development, influencing the morphological and physiological characteristics of plants by modulating biological processes. While studies on plant melatonin receptors are in their early stages compared to studies in animal receptors, the binding mechanism with melatonin is now recognized… More >

Kai Kang^1,*, Zhiyong Wang^2,3

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.3, pp. 1-1, 2025, DOI:10.32604/icces.2025.012678

Abstract Terahertz time-domain spectroscopy (THz-TDS) can be utilized to probe internal parameters of dielectric materials, such as the refractive index. Based on the stress-optic law, stress-induced variations in the refractive index enable the calculation of applied stress through measured changes in the refractive index. This paper introduces a THz-TDS-based methodology for stress field measurement. First, a THz-TDS stress field scanning and imaging system was developed, incorporating an amplitude-field imaging method that maps stress distributions using variations in the amplitude of THz pulses. Second, two analytical algorithms were established: a planar stress analysis algorithm based on THz… More >

Qiuze Yao, Zhensheng Wu, Xiang Peng^*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.2, pp. 1-1, 2025, DOI:10.32604/icces.2025.011507

Abstract Fiber-reinforced composites are widely applied in various fields due to their high strength and modulus, and analyzing their physical field is crucial for improving material performance and structural design. However, traditional analysis methods, such as finite element analysis (FEM) and numerical computation are still limited by computational efficiency and accuracy when applied to microstructures. To address this challenge, convolutional neural network (CNN) approaches are being developed to quickly and accurately predict the physical fields in fiber-reinforced composites. Under static loading, the U-Net framework is developed with an adaptive two-stage training approach to address the generalization… More >

Farhat Abbas¹, Fahim Ullah Khan^1,2,*, Salem Al-Naemi³, Awni Al-Otoom¹, Ahmed T. Moustafa⁴, Khaled Shami¹

Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2911-2925, 2025, DOI:10.32604/phyton.2025.064239 - 30 September 2025

Abstract This study aimed to explore the relationship between Soil-Plant Analysis Development (SPAD) values and key environmental factors in cucumber (Cucumis sativus L.) cultivation in a greenhouse. SPAD values, indicative of chlorophyll content, reflect plant health and productivity. The analysis revealed strong positive correlations between SPAD values and both indoor light intensity (ILI, r = 0.59, p < 0.001) and outdoor light intensity (OLI, r = 0.62, p < 0.001), suggesting that higher light intensities were associated with enhanced SPAD values. In contrast, significant negative correlations were found between SPAD values and soil temperature at 15–30 cm depth… More >

Pasqualino Corigliano^*, Giulia Palomba

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 1935-1955, 2025, DOI:10.32604/cmes.2025.067094 - 31 August 2025

Abstract Experimental tests are essential for evaluating S-N curves and assessing the fatigue life of welded joints. However, in the case of complex geometries, experimental tests often cannot provide the necessary stress-strain data for specific materials and welded joints. Therefore, finite element (FE) analyses are frequently utilized to assess fatigue behavior in complex geometries and address the discontinuities induced by welding processes. In this study, the fatigue properties of titanium welded joints, produced using an innovative laser source and welded without the use of filler materials, were analyzed through numerical methods. Two different FE methods were… More >

Qizhi Chen^1,2, Wensheng Cheng^1,2, Baoping Zou^1,2,*, Bowen Kong^1,2, Yansheng Deng^1,2, Xu Long^3,*

Journal of Polymer Materials, Vol.42, No.2, pp. 463-475, 2025, DOI:10.32604/jpm.2025.064257 - 14 July 2025

Abstract The rapid development of urban rail transit has posed increasing construction and operational challenges for metro tunnels, often leading to structural damage. Grouting technology using cement-based materials is widely applied to address issues such as seepage, leakage, and alignment correction in shield tunnels. This study investigates the additional stress induced by grouting in silty soil layers, using cement-based grouts with different water-to-cement ratios and polyurethane-modified cement-based materials. Results show that additional stress decreases with depth and is more influenced by horizontal distance from the grouting point. In staged grouting, the first injection phase contributes about More >

Chunling Yan^1,2, Renzhang Yan^1,2,*, Zhenxiu Zhan¹, Xiyang Chen¹, Yu Han³

Structural Durability & Health Monitoring, Vol.19, No.4, pp. 1037-1056, 2025, DOI:10.32604/sdhm.2025.058780 - 30 June 2025

Abstract The steel tube arch rib in a large-span concrete-filled steel tube arch bridge has a large span and diameter, which also leads to a larger weld seam scale. Large-scale welding seams will inevitably cause more obvious welding residual stress (WRS). For the purpose of studying the influence of WRS from large-scale welding seam on the mechanical properties of steel tube arch rib during arch rib splicing, test research and numerical simulation analysis on the WRS in arch rib splicing based on the Guangxi Pingnan Third Bridge, which is the world’s largest span concrete-filled steel… More >