MINGZHI LUO*, KAI NI, YAN SUN, JIA GUO, KANG WEN, LINHONG DENG*
BIOCELL, Vol.46, No.4, pp. 855-871, 2022, DOI:10.32604/biocell.2022.017520
- 15 December 2021
Abstract Coronavirus disease 2019 (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is still threatening the human life and society throughout the world. For those critically ill patients, mechanical ventilation (MV) is essential to provide life support during treatment. However, both the virus infection and MV disrupt the balance between secretion and elimination of airway mucus and lead to mucus accumulation in the lung. Postmortem examination verified that the lungs in patients died of COVID-19 are indeed filled with sticky mucus, suggesting a great need to improve airway mucus clearance in critically ill COVID-19 patients. More >
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