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  • Open Access

    ARTICLE

    The cost and guideline adherence of direct-to-consumer telemedicine companies offering gender-affirming hormone therapy

    Nicholas Sellke1,2,*, Erin Jesse1,2, Justin M. Dubin3, Tomislav D. Medved1,2, Neha S. Basti4, Janvi Ramchandra2, Robert E. Brannigan4, Joshua A. Halpern4, Nannan Thirumavalavan1,2

    Canadian Journal of Urology, Vol.32, No.2, pp. 89-94, 2025, DOI:10.32604/cju.2025.065004 - 30 April 2025

    Abstract Introduction: Direct-to-consumer (DTC) telemedicine has emerged as an option for transgender patients seeking gender affirming hormone therapy (GAHT). We aimed to characterize the healthcare services provided by DTC telemedicine companies offering GAHT and to compare their costs to a tertiary care center. Methods: We identified DTC telemedicine platforms offering GAHT via internet searches and extracted information from their websites related to evaluation, treatment, monitoring, and cost. Cost of the DTC GAHT was compared to cost for comparable services at a tertiary care center. Results: Six DTC companies were identified. All platforms utilized an informed consent model… More >

  • Open Access

    ARTICLE

    Mind matters: how anxiety and depression shape low-risk prostate cancer active surveillance adherence in a real-world population

    Zachariah Taylor1,*, Kayla Meyer2, Danielle Terrenzio2, Ryan Wong3, Sharon Larson4, Stephanie Kjelstrom4, Natalina Contoreggi5, Laurence Belkoff1,6, Ilia Zeltser1,6

    Canadian Journal of Urology, Vol.32, No.1, pp. 21-27, 2025, DOI:10.32604/cju.2025.064705 - 20 March 2025

    Abstract Purpose: While the mental health impact of a prostate cancer diagnosis, including low-risk prostate cancer, is well-documented, the effect of pre-existing anxiety and/or depression on adherence to active surveillance protocols in low-risk prostate cancer patients remains unclear. This study assessed the association between prior anxiety and/or depression and active surveillance adherence in men with low-risk prostate cancer. Methods: We conducted a retrospective, multicenter study involving 426 men diagnosed with low-risk prostate cancer who were recommended active surveillance as the primary management strategy. Active surveillance adherence was defined by completion of both a prostate-specific antigen test… More >

  • Open Access

    ARTICLE

    Self-Reported Adherence to Capecitabine on XELOX Treatment as Adjuvant Therapy for Colorectal Cancer

    Kazuyoshi Kawakami*, Takashi Yokokawa*, Kazuo Kobayashi*, Takahito Sugisaki*, Kenichi Suzuki*, Mitsukuni Suenaga, Kensei Yamaguchi, Ayaka Inoue, Yoshiaki Machida, Toshiharu Yamaguchi, Toshihiro Hama*

    Oncology Research, Vol.25, No.9, pp. 1625-1631, 2017, DOI:10.3727/096504017X15012905098071

    Abstract Adherence has become an important issue in modern oncology treatment. Most studies have included heterogeneous target tumor types, regimens, and therapy settings. Our study focused on capecitabine during capecitabine plus oxaliplatin (XELOX) treatment as an adjuvant therapy for colorectal cancer. The main aims of this study were to evaluate real-life adherence to capecitabine and to investigate candidate factors that might decrease adherence. We studied 338 consecutive patients who received XELOX treatment between December 1, 2011, and April 30, 2015, at the Cancer Institute Hospital of the Japanese Foundation for Cancer Research. Our study assessed adherence… More >

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