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  • Open Access

    REVIEW

    Research Progress on Plant Anti-Freeze Proteins

    Zhengyang Zhang#, Weixue Liu#, Yinran Huang*, Ping Li*

    Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1263-1274, 2024, DOI:10.32604/phyton.2024.050755

    Abstract Plant antifreeze proteins (AFPs) are special proteins that can protect plant cells from ice crystal damage in low-temperature environments, and they play a crucial role in the process of plants adapting to cold environments. Proteins with these characteristics have been found in fish living in cold regions, as well as many plants and insects. Although research on plant AFPs started relatively late, their application prospects are broad, leading to the attention of many researchers to the isolation, cloning, and genetic improvement of plant AFP genes. Studies have found that the distribution of AFPs in different species… More >

  • Open Access

    ARTICLE

    Influence of Polyaluminum Chloride Residue on the Strength and Microstructure of Cement-Based Materials

    Ping Xu1,*, Zhiwei Zhang1, Zhenguo Hou2,3, Mankui Zheng1, Jin Tong1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1299-1312, 2024, DOI:10.32604/fdmp.2023.046183

    Abstract In this paper, cement and dechlorinated Polyaluminum Chloride Residue (PACR) have been used to prepare a net slurry and mortar specimens. Two hydration activity indicators have been used to quantitatively analyze the dechlorinated PACR hydration activity. In particular, the effect of dechlorinated PACR content on the compressive strength of mortar has been assessed by means of compressive strength tests. Moreover, X-ray diffraction (XRD) and scanning electron microscopy (SEM) have been employed to observe the microstructure of the considered hydration products. The following results have been obtained. The 28th day activity index of the dechlorinated PACR… More >

  • Open Access

    ARTICLE

    Coupling Analysis of Multiple Machine Learning Models for Human Activity Recognition

    Yi-Chun Lai1, Shu-Yin Chiang2, Yao-Chiang Kan3, Hsueh-Chun Lin4,*

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 3783-3803, 2024, DOI:10.32604/cmc.2024.050376

    Abstract Artificial intelligence (AI) technology has become integral in the realm of medicine and healthcare, particularly in human activity recognition (HAR) applications such as fitness and rehabilitation tracking. This study introduces a robust coupling analysis framework that integrates four AI-enabled models, combining both machine learning (ML) and deep learning (DL) approaches to evaluate their effectiveness in HAR. The analytical dataset comprises 561 features sourced from the UCI-HAR database, forming the foundation for training the models. Additionally, the MHEALTH database is employed to replicate the modeling process for comparative purposes, while inclusion of the WISDM database, renowned… More > Graphic Abstract

    Coupling Analysis of Multiple Machine Learning Models for Human Activity Recognition

  • Open Access

    ARTICLE

    Identification of Secondary Metabolites in Tunisian Tilia platyphyllos Scop. Using MALDI-TOF and GC-MS

    Ayda Khadhri1, Mohamed Mendili1, Marwa Bannour-Scharinger1, Eric Masson2, Antonio Pizzi2,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 827-842, 2024, DOI:10.32604/jrm.2024.046950

    Abstract This study is the first to evaluate the phytochemical content and biological properties of Tunisian T. platyphyllos Scop. A total of 23 compounds of essential oils were identified by gas chromatography-mass spectrometry (GC-MS) analysis of bracts and fruit extracts. The results show that oxygenated monoterpenes were the dominant class of essential oils. The phenolic composition was investigated by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). The analysis showed that the chemical profiles of the ethanolic extracts of bracts and fruits are substantially similar. The highest polyphenol content was found in the ethanolic extracts of the fruits (7.65… More > Graphic Abstract

    Identification of Secondary Metabolites in Tunisian <i>Tilia platyphyllos</i> Scop. Using MALDI-TOF and GC-MS

  • Open Access

    ARTICLE

    Investigation of Cavitation in NaCl Solutions in a Sonochemical Reactor Using the Foil Test Method

    Michael Kuchinskiy1,2,*, Tatyana Lyubimova1,2, Konstantin Rybkin2, Anastasiia Sadovnikova2, Vasiliy Galishevskiy2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1093-1102, 2024, DOI:10.32604/fdmp.2024.050059

    Abstract Ultrasonic baths and sonochemical reactors are widely used in industrial applications dealing with surface cleaning and chemical synthesis. The processes of erosion, cleaning and structuring of the surface can be typically controlled by changing relevant influential parameters. In particular, in this work, we experimentally investigate the effect of NaCl concentration (0–5.5 mol/L) on the erosion of an aluminum foil under ultrasonic exposure at a frequency of 28 kHz. Special attention is paid to the determination of cavitation zones and their visualization using heat maps. It is found that at low NaCl concentration (0.3 mol/L), the More > Graphic Abstract

    Investigation of Cavitation in NaCl Solutions in a Sonochemical Reactor Using the Foil Test Method

  • Open Access

    ARTICLE

    Association between Meeting 24-Hour Movement Guidelines and Psychological Features of Chinese Emerging Adults

    Yanjie Zhang1,2, Jin Kuang3, Xun Luo1,2, Mengxian Zhao4, Xiaolei Liu5,*

    International Journal of Mental Health Promotion, Vol.26, No.5, pp. 399-406, 2024, DOI:10.32604/ijmhp.2024.048925

    Abstract Background: Emerging adulthood is a pivotal life stage, presenting significant psychological and social changes, such as decreased sociability, depression, and other mental health problems. Previous studies have associated these changes with an unhealthy lifestyle. The 24-h movement guidelines for healthy lifestyles have been developed to promote appropriate health behaviors and improve individual wellness. However, the relationship between adherence to the 24-h movement guidelines and different characteristics of Chinese emerging adults is yet to be explored. This cross-sectional study aimed to investigate the association between adherence to the 24-h movement guidelines and four characteristics (self-exploration, instability, possibilities,… More >

  • Open Access

    ARTICLE

    Inhibitors of PI3K/ERK1/2/p38 MAPK Show Preferential Activity Against Endocrine-Resistant Breast Cancer Cells

    Maitham A. Khajah, Princy M. Mathew, Yunus A. Luqmani

    Oncology Research, Vol.25, No.8, pp. 1283-1295, 2017, DOI:10.3727/096504017X14883245308282

    Abstract Current mainstream pharmacological options for the treatment of endocrine-resistant breast cancer have limitations in terms of their side effect profile and lack of discrimination between normal and cancer cells. In the current study, we assessed the responses of normal breast epithelial cells MCF10A, estrogen receptorpositive (ER+ ) MCF-7, and ER-silenced pII breast cancer cells to inhibitors (either individually or in combination) of downstream signaling molecules. The expression/activity of ERK1/2, p38 MAPK, and Akt was determined by Western blotting. Cell proliferation, motility, and invasion were determined using MTT, wound healing, and Matrigel assays, respectively. Morphological changes… More >

  • Open Access

    ARTICLE

    Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo

    Antonello Di Paolo1, Paola Orlandi1, Teresa Di Desidero, Romano Danesi, Guido Bocci

    Oncology Research, Vol.25, No.7, pp. 1129-1140, 2017, DOI:10.3727/096504017X14841698396900

    Abstract The combination of folinate salts to 5-fluoruracil (5-FU)-based schedules is an established clinical routine in the landscape of colorectal cancer treatment. The aim of this study was to investigate the pharmacological differences between the sequential administration of folinate salts (1 h before, as in clinical routine) followed by 5-FU and the simultaneous administration of both drugs. Proliferation and apoptotic assays were performed on human colon cancer cells exposed to 5-FU, calcium (CaLV), or disodium (NaLV) levofolinate or their simultaneous and sequential combination for 24 and 72 h. TYMS and SLC19A1 gene expression was performed with… More >

  • Open Access

    ARTICLE

    Knockdown of Ras-Related Protein 25 (Rab25) Inhibits the In Vitro Cytotoxicity and In Vivo Antitumor Activity of Human Glioblastoma Multiforme Cells

    Bingqian Ding1, Bei Cui1, Ming Gao, Zhenjiang Li, Chenyang Xu, Shaokang Fan, Weiya He

    Oncology Research, Vol.25, No.3, pp. 331-340, 2017, DOI:10.3727/096504016X14736286083065

    Abstract Ras-related protein 25 (Rab25) is a member of the Rab family, and it has been reported to play an important role in tumorigenesis. However, its direct involvement in human glioblastoma multiforme (GBM) is still unclear. The aim of the current study was to investigate the potential role of Rab25 in the growth, proliferation, invasion, and migration of human GBM. Our results showed that Rab25 expression was significantly higher in human GBM cell lines compared with a normal astrocyte cell line. In vitro functional studies revealed that knockdown of Rab25 reduced cell proliferation and inhibited invasion More >

  • Open Access

    ARTICLE

    Three New Hydroxytetradecenals from Amomum tsao-ko with Protein Tyrosine Phosphatase 1B and Glycogen Phosphorylase Inhibitory Activity

    Xiaolu Qin1,3, Xinyu Li1,3, Yi Yang2, Mei Huang2, Shengli Wu1, Pianchou Gongpan1, Lianzhang Wu2, Juncai He2, Changan Geng1,3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 875-883, 2024, DOI:10.32604/phyton.2024.048192

    Abstract The fruits of Amomum tsao-ko (Cao-Guo) were documented in Chinese Pharmacopoeia for the treatment of abdominal pain, vomiting, and plague. In our previous study, a series of diarylheptanes and flavonoids with α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activity have been reported from the middle-polarity part of A. tsao-ko, whereas the antidiabetic potency of the low-polarity constituents is still unclear. In this study, three new hydroxytetradecenals, (2E, 4E, 8Z, 11Z)-6R-hydroxytetradeca-2,4,8,11-tetraenal (1), (2E, 4E, 8Z)-6R-hydroxytetradeca-2,4,8-trienal (2) and (2E, 4E)-6R-hydroxytetradeca-2,4-dienal (3) were obtained from the volatile oils of A. tsao-ko. The structures of compounds 1–3 were determined using spectroscopic data involving 1D and 2D nuclear magnetic More >

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