Jesus Sebastian DISTEL1, Walter BERON1, Rodolfo Matias ORTIZ FLORES1,2
BIOCELL, Vol.43, No.1, pp. 1-6, 2019, DOI:10.32604/biocell.2019.07021
Abstract Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding of C. burnetii invasion and its survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of C. burnetii, and we discuss the contribution of diverse degradation pathways of the cell during the formation and stabilization of the Coxiella-containing vacuole. More >
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