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  • Open Access

    REVIEW

    The Transparency Revolution in Geohazard Science: A Systematic Review and Research Roadmap for Explainable Artificial Intelligence

    Moein Tosan1,*, Vahid Nourani2,3, Ozgur Kisi4,5,6, Yongqiang Zhang7, Sameh A. Kantoush8, Mekonnen Gebremichael9, Ruhollah Taghizadeh-Mehrjardi10, Jinhui Jeanne Huang11

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074768 - 29 January 2026

    Abstract The integration of machine learning (ML) into geohazard assessment has successfully instigated a paradigm shift, leading to the production of models that possess a level of predictive accuracy previously considered unattainable. However, the black-box nature of these systems presents a significant barrier, hindering their operational adoption, regulatory approval, and full scientific validation. This paper provides a systematic review and synthesis of the emerging field of explainable artificial intelligence (XAI) as applied to geohazard science (GeoXAI), a domain that aims to resolve the long-standing trade-off between model performance and interpretability. A rigorous synthesis of 87 foundational… More >

  • Open Access

    ARTICLE

    Several Improved Models of the Mountain Gazelle Optimizer for Solving Optimization Problems

    Farhad Soleimanian Gharehchopogh*, Keyvan Fattahi Rishakan

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.073808 - 29 January 2026

    Abstract Optimization algorithms are crucial for solving NP-hard problems in engineering and computational sciences. Metaheuristic algorithms, in particular, have proven highly effective in complex optimization scenarios characterized by high dimensionality and intricate variable relationships. The Mountain Gazelle Optimizer (MGO) is notably effective but struggles to balance local search refinement and global space exploration, often leading to premature convergence and entrapment in local optima. This paper presents the Improved MGO (IMGO), which integrates three synergistic enhancements: dynamic chaos mapping using piecewise chaotic sequences to boost exploration diversity; Opposition-Based Learning (OBL) with adaptive, diversity-driven activation to speed up… More >

  • Open Access

    ARTICLE

    Research on Deformation Mechanism of Rolled AZ31B Magnesium Alloy during Tension by VPSC Model Computational Simulation

    Xun Chen1, Jinbao Lin1,2,*, Zai Wang1

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072495 - 12 January 2026

    Abstract This work investigates the effects of deformation mechanisms on the mechanical properties and anisotropy of rolled AZ31B magnesium alloy under uniaxial tension, combining experimental characterization with Visco-Plastic Self Consistent (VPSC) modeling. The research focuses particularly on anisotropic mechanical responses along transverse direction (TD) and rolling direction (RD). Experimental measurements and computational simulations consistently demonstrate that prismatic <a> slip activation significantly reduces the strain hardening rate during the initial stage of tensile deformation. By suppressing the activation of specific deformation mechanisms along RD and TD, the tensile mechanical behavior of the magnesium alloy was further investigated. More >

  • Open Access

    ARTICLE

    Numerical Analysis of Non-Uniform Pollutant Distribution in an Internal Space of Tank and the Efficacy of an Active Purification Strategy

    Xiaolong Li, Hui Chen, Yingwen Liu, Peng Yang*

    Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 1767-1788, 2025, DOI:10.32604/fhmt.2025.070537 - 31 December 2025

    Abstract Hazardous gas intrusion in tightly sealed and geometrically complex confined spaces, such as armored tanks, poses a critical threat to occupant health. The intricate internal structure of these systems may lead to non-intuitive pollutant transport pathways. However, the spatial and temporal evolution of these structures, as well as the intrinsic mechanisms of the purification systems, remain poorly elucidated. In this study, a high-fidelity, transient three-dimensional computational fluid dynamics (CFD) model was developed to simulate the leakage and dispersion of carbon monoxide (CO) and nitrogen dioxide (NO2) using the RNG k-ε turbulence model. Scenarios with and without… More > Graphic Abstract

    Numerical Analysis of Non-Uniform Pollutant Distribution in an Internal Space of Tank and the Efficacy of an Active Purification Strategy

  • Open Access

    ARTICLE

    Targeting HER2-Positive HCC1954 Breast Cancer Cells by Novel Thiazole-Dihydrobenzisoxazoles: In-Depth Design, Synthesis and Initial In Vitro Study

    Yuri A. Piven1, Danila V. Sorokin2, Nastassia A. Varabyeva1, Alexandra L. Mikhaylova2, Fedor B. Bogdanov2, Elena V. Shafranovskaya1, Raman M. Puzanau3, Fedor A. Lakhvich1, Alexander M. Scherbakov2,4,*

    Oncology Research, Vol.33, No.12, pp. 4049-4072, 2025, DOI:10.32604/or.2025.067832 - 27 November 2025

    Abstract Background: The most aggressive forms of breast cancer are characterized by independence from steroid hormones but a strong dependence on growth factors. In such cancer cells, oncogenic receptors, including human epidermal growth factor receptor 2 (HER2), are activated, and their targeted inhibition represents an attractive therapeutic strategy. The study aimed to develop small-molecule potential dual heat shock protein 90 (HSP90)-HER2 inhibitors and evaluate them as anticancer agents in HER2-positive cells. Methods: The research project involved obtaining a series of compounds with potential dual inhibitory activity against HSP90 and HER2 by targeted organic synthesis, which was… More > Graphic Abstract

    Targeting HER2-Positive HCC1954 Breast Cancer Cells by Novel Thiazole-Dihydrobenzisoxazoles: In-Depth Design, Synthesis and Initial <i>In Vitro</i> Study

  • Open Access

    ARTICLE

    Joint Estimation of Elevation and Azimuth Angles with Triple-Parallel ULAs Using Metaheuristic and Direct Search Methods

    Fawad Zaman1,#, Adeel Iqbal2,#, Bakhtiar Ali1, Abdul Khader Jilani Saudagar3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2535-2550, 2025, DOI:10.32604/cmes.2025.072638 - 26 November 2025

    Abstract Accurate estimation of the Direction-of-Arrival (DoA) of incident plane waves is essential for modern wireless communication, radar, sonar, and localization systems. Precise DoA information enables adaptive beamforming, spatial filtering, and interference mitigation by steering antenna array beams toward desired sources while suppressing unwanted signals. Traditional one-dimensional Uniform Linear Arrays (ULAs) are limited to elevation angle estimation due to geometric constraints, typically within the range [0, π]. To capture full spatial characteristics in environments with multipath and angular spread, joint estimation of both elevation and azimuth angles becomes necessary. However, existing 2D and 3D array geometries… More >

  • Open Access

    ARTICLE

    Automatic Potential Safety Hazard Detection for High-Speed Railroad Surrounding Environment Using Lightweight Hybrid Dual Tasks Architecture

    Zheda Zhao, Tao Xu, Tong Yang, Yunpeng Wu*, Fengxiang Guo*

    Structural Durability & Health Monitoring, Vol.19, No.6, pp. 1457-1472, 2025, DOI:10.32604/sdhm.2025.069611 - 17 November 2025

    Abstract Utilizing unmanned aerial vehicle (UAV) photography to timely detect and evaluate potential safety hazards (PSHs) around high-speed rail has great potential to complement and reform the existing manual inspections by providing better overhead views and mitigating safety issues. However, UAV inspections based on manual interpretation, which heavily rely on the experience, attention, and judgment of human inspectors, still inevitably suffer from subjectivity and inaccuracy. To address this issue, this study proposes a lightweight hybrid learning algorithm named HDTA (hybrid dual tasks architecture) to automatically and efficiently detect the PSHs of UAV imagery. First, this HDTA… More >

  • Open Access

    ARTICLE

    Some Important Features of the Lambert Equivalent Azimuthal Projection

    Miljenko Lapaine*

    Revue Internationale de Géomatique, Vol.34, pp. 793-808, 2025, DOI:10.32604/rig.2025.066916 - 06 November 2025

    Abstract The paper investigates the properties of the Lambert equivalent azimuthal projection, which is often used in normal aspect in atlases for maps of the northern and southern hemispheres. The field of research is theoretical in nature and assumes a mastery of mathematics because it deals with map projections. The transverse aspect is commonly used for eastern and western hemisphere atlas maps. In addition, the Hammer projection was created from the transverse aspect of that projection. Therefore, if we want to get to know the Hammer projection better, we must first investigate the Lambert equivalent azimuthal… More >

  • Open Access

    ARTICLE

    Short-Term Multi-Hazard Prediction Using a Multi-Source Data Fusion Approach

    Syeda Zoupash Zahra1, Najia Saher2, Malik Muhammad Saad Missen3, Rab Nawaz Bashir4,5, Salma Idris5, Tahani Jaser Alahmadi6,*, Muhammad Inshal Khan5

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4869-4883, 2025, DOI:10.32604/cmc.2025.067639 - 23 October 2025

    Abstract The increasing frequency and intensity of natural disasters necessitate advanced prediction techniques to mitigate potential damage. This study presents a comprehensive multi-hazard early warning framework by integrating the multi-source data fusion technique. A multi-source data extraction method was introduced by extracting pressure level and average precipitation data based on the hazard event from the Cooperative Open Online Landslide Repository (COOLR) dataset across multiple temporal intervals (12 h to 1 h prior to events). Feature engineering was performed using Choquet fuzzy integral-based importance scoring, which enables the model to account for interactions and uncertainty across multiple… More >

  • Open Access

    ARTICLE

    Tetramethylpyrazine Alleviates Pancreatitis Progression by Regulating Inflammation and Autophagy through the YAP-RIPK1-NF-κB Axis

    Hong Wu, Yang Liu*

    BIOCELL, Vol.49, No.10, pp. 1985-2006, 2025, DOI:10.32604/biocell.2025.069527 - 22 October 2025

    Abstract Background: Acute pancreatitis (AP) is a serious gastrointestinal disorder. Tetramethylpyrazine (TMP), a bioactive alkaloid extracted from Ligusticum chuanxiong, exhibits various pharmacological effects, but its protective mechanisms against AP remain unclear. This study aimed to investigate the protective effects and underlying mechanisms of TMP in AP. Methods: The study utilized Cerulein (CER) to model pancreatitis across experimental systems. Cellular responses were characterized through functional assays (CCK-8 viability, EdU proliferation, Transwell migration, flow cytometric apoptosis, Fluo-3/AM calcium imaging) and inflammatory profiling (ELISA for trypsin, CRP, TNF-α, IL-1β, IL-6). Autophagy was monitored via mRFP-GFP-LC3 flux and LysoTracker staining, with… More > Graphic Abstract

    Tetramethylpyrazine Alleviates Pancreatitis Progression by Regulating Inflammation and Autophagy through the YAP-RIPK1-NF-<b>κ</b>B Axis

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