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  • Open Access

    REVIEW

    Do tensile and shear forces exerted on cells influence mechanotransduction through stored energy considerations?

    FREDERICK H. SILVER1,2,*, TANMAY DESHMUKH2

    BIOCELL, Vol.48, No.4, pp. 525-540, 2024, DOI:10.32604/biocell.2024.047965

    Abstract All tissues in the body are subjected externally to gravity and internally by collagen fibril and cellular retractive forces that create stress and energy equilibrium required for homeostasis. Mechanotransduction involves mechanical work (force through a distance) and energy storage as kinetic and potential energy. This leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue components. It involves the application of energy directly to cells through integrin-mediated processes, cell-cell connections, stretching of the cell cytoplasm, and activation of the cell nucleus via yes-associated protein (YAP) and transcriptional coactivator with PDZ-motif (TAZ). These processes involve numerous… More >

  • Open Access

    ARTICLE

    Gp78 regulates PMP22 and causes ER stress and autophagy in EV71-VP1-overexpressing mouse Schwann cells

    DANPING ZHU1,#, GUANGMING LIU1,#, KUAN FENG1, SUYUN LI1, DANDAN HU2, SIDA YANG3,*, PEIQING LI1,*

    BIOCELL, Vol.48, No.4, pp. 653-664, 2024, DOI:10.32604/biocell.2024.044856

    Abstract Background: During Enterovirus type 71 (EV71) infection, the structural viral protein 1 (VP1) activates endoplasmic reticulum (ER) stress associated with peripheral myelin protein 22 (PMP22) accumulation and induces autophagy. However, the specific mechanism behind this process remains elusive. Methods: In this research, we used the VP1-overexpressing mouse Schwann cells (SCs) models co-transfected with a PMP22 silencing or Autocrine motility factor receptor (AMFR/gp78) overexpressing vector to explore the regulation of gp78 on PMP22 and its relationship with autophagy and apoptosis. Results: The activity of gp78 could be influenced by EV71-VP1, leading to a decrease in the ubiquitination and degradation of PMP22,… More >

  • Open Access

    ARTICLE

    Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF)-Mass Spectrometry and 13C-NMR-Identified New Compounds in Paraberlinia bifoliolata (Ekop-Beli) Bark Tannins

    Liliane Nga1, Benoit Ndiwe1,2, Achille Bernard Biwolé1, Antonio Pizzi3,*, Jean Jalin Eyinga Biwole1, Joseph Zobo Mfomo1

    Journal of Renewable Materials, Vol.12, No.3, pp. 553-568, 2024, DOI:10.32604/jrm.2023.046568

    Abstract Extracts of plant origin, particularly tannins, are attracting growing interest for the sustainable development of materials in the industrial sector. The discovery of new tannins is therefore necessary. The aim of this work was to contribute to the understanding of the properties of Paraberlinia bifoliolata tannin by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy MALDI-TOF/MS and Carbon 13 Nuclear Magnetic Resonance (13C NMR). The chemical composition of tannin extracted from Paraberlinia bifoliolata bark was determined, as was the mechanical strength of the resin hardened with Acacia nilotica extracts. Yield by successive water extraction was 35%. MALDI-TOF/MS analysis… More >

  • Open Access

    REVIEW

    A Review on Sources, Extractions and Analysis Methods of a Sustainable Biomaterial: Tannins

    Antonio Pizzi1,*, Marie-Pierre Laborie2,3, Zeki Candan4

    Journal of Renewable Materials, Vol.12, No.3, pp. 397-425, 2024, DOI:10.32604/jrm.2023.046074

    Abstract Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products. They are a definite class of sustainable materials of the forestry industry. They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries, such as wood adhesives, metal coating, pharmaceutical/medical applications and several others. This review presents the main sources, either already or potentially commercial of this forestry by-materials, their industrial… More > Graphic Abstract

    A Review on Sources, Extractions and Analysis Methods of a Sustainable Biomaterial: Tannins

  • Open Access

    ARTICLE

    Mathematical Modelling and Simulations of Active Direct Methanol Fuel Cell

    RABIRANJAN MURMUa,b, DEBASHIS ROYa, HAREKRUSHNA SUTARb

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 125-139, 2023, DOI:10.32381/JPM.2023.40.3-4.1

    Abstract A one dimensional isothermal model is proposed by modelling the kinetics of methanol transport at anode flow channel (AFC), membrane and cathode catalyst layer of direct methanol fuel cell (DMFC). Analytical model is proposed to predict methanol cross-over rate through the electrolyte membrane and cell performance. The model presented in this paper considered methanol diffusion and electrochemical oxidation at the anode and cathode channels. The analytical solution of the proposed model was simulated in a MATLAB environment to obtain the polarization curve and leakage current. The effect of methanol concentration on cell voltage and leakage current is studied. The methanol… More >

  • Open Access

    ARTICLE

    Study of Galvanic Charging-Discharging Properties of Graphene Nanoplatelets Incorporated Epoxy-Carbon Fabric Composites

    HADIMANI SHIVAKUMAR1, GURUMURTHY G. D.1, BOMMEGOWDA K. B.2, S. PARAMESHWARA3

    Journal of Polymer Materials, Vol.40, No.1-2, pp. 93-103, 2023, DOI:10.32381/JPM.2023.40.1-2.8

    Abstract Polymer composites are increasing in demand in energy storage applications including in the electronic as well as electrical industries due to the ease of processing of these materials with associated advantages like light weight, corrosion resistance, and high mechanical strength. In this investigation, efforts are made to enhance the charging and discharging properties of epoxy/carbon fabric composite by the addition of graphene nanoplatelets (GNPs) into the epoxy/ carbon matrix. The performance of the composites with graphene platelets of 0.5 to 5 wt. % in epoxy were characterized and 1wt.% percolation threshold was observed poor performance in gravimetric charge and discharge… More >

  • Open Access

    ARTICLE

    Microscopic Analysis of Cementitious Sand and Gravel Damming Materials

    Ran Wang1, Aimin Gong1,*, Shanqing Shao1, Baoli Qu2, Jing Xu3, Fulai Wang1, Feipeng Liu3,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.4, pp. 749-769, 2024, DOI:10.32604/fdmp.2023.042566

    Abstract The mechanical properties of cementitious sand and gravel damming material have been experimentally determined by means of microscopic SEM (Scanning Electron Microscopy) image analysis. The results show that the combination of fly ash and water can fill the voids in cemented sand and gravel test blocks because of the presence of hydrated calcium silicate and other substances; thereby, the compactness and mechanical properties of these materials can be greatly improved. For every 10 kg/m3 increase in the amount of cementitious material, the density increases by about 2%, and the water content decreases by 0.2%. The amount of cementitious material used… More > Graphic Abstract

    Microscopic Analysis of Cementitious Sand and Gravel Damming Materials

  • Open Access

    ARTICLE

    Unmanned Aerial Vehicles General Aerial Person-Vehicle Recognition Based on Improved YOLOv8s Algorithm

    Zhijian Liu*

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3787-3803, 2024, DOI:10.32604/cmc.2024.048998

    Abstract Considering the variations in imaging sizes of the unmanned aerial vehicles (UAV) at different aerial photography heights, as well as the influence of factors such as light and weather, which can result in missed detection and false detection of the model, this paper presents a comprehensive detection model based on the improved lightweight You Only Look Once version 8s (YOLOv8s) algorithm used in natural light and infrared scenes (L_YOLO). The algorithm proposes a special feature pyramid network (SFPN) structure and substitutes most of the neck feature extraction module with the Special deformable convolution feature extraction module (SDCN). Moreover, the model… More >

  • Open Access

    ARTICLE

    Hybrid Optimization Algorithm for Handwritten Document Enhancement

    Shu-Chuan Chu1, Xiaomeng Yang1, Li Zhang2, Václav Snášel3, Jeng-Shyang Pan1,4,*

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3763-3786, 2024, DOI:10.32604/cmc.2024.048594

    Abstract The Gannet Optimization Algorithm (GOA) and the Whale Optimization Algorithm (WOA) demonstrate strong performance; however, there remains room for improvement in convergence and practical applications. This study introduces a hybrid optimization algorithm, named the adaptive inertia weight whale optimization algorithm and gannet optimization algorithm (AIWGOA), which addresses challenges in enhancing handwritten documents. The hybrid strategy integrates the strengths of both algorithms, significantly enhancing their capabilities, whereas the adaptive parameter strategy mitigates the need for manual parameter setting. By amalgamating the hybrid strategy and parameter-adaptive approach, the Gannet Optimization Algorithm was refined to yield the AIWGOA. Through a performance analysis of… More >

  • Open Access

    ARTICLE

    Path Planning for AUVs Based on Improved APF-AC Algorithm

    Guojun Chen*, Danguo Cheng, Wei Chen, Xue Yang, Tiezheng Guo

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3721-3741, 2024, DOI:10.32604/cmc.2024.047325

    Abstract With the increase in ocean exploration activities and underwater development, the autonomous underwater vehicle (AUV) has been widely used as a type of underwater automation equipment in the detection of underwater environments. However, nowadays AUVs generally have drawbacks such as weak endurance, low intelligence, and poor detection ability. The research and implementation of path-planning methods are the premise of AUVs to achieve actual tasks. To improve the underwater operation ability of the AUV, this paper studies the typical problems of path-planning for the ant colony algorithm and the artificial potential field algorithm. In response to the limitations of a single… More >

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