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  • Open Access

    ARTICLE

    Abaca Fiber as a Potential Reinforcer for Acoustic Absorption Material at Middle-High Frequencies

    Susilo Indrawati*, Lila Yuwana, Suyatno, Mochamad Zainuri, Darminto*

    Journal of Renewable Materials, Vol.12, No.5, pp. 909-921, 2024, DOI:10.32604/jrm.2024.048452

    Abstract Recently, abaca fibers have become the focus of specialized research due to their intriguing characteristics, with their outstanding mechanical properties being a particularly notable. In the conducted study, the abaca fibers underwent a preliminary treatment process involving an alkaline solution, which was composed of 0.5% sodium hydroxide (NaOH) and 50% acetic acid (CHCOOH). This process entailed immersing each fiber in the solution for a period of one hour. This treatment led to a 52.36% reduction in lignin content compared to the levels before treatment, resulting in a dramatic decrease in the full width at half… More > Graphic Abstract

    Abaca Fiber as a Potential Reinforcer for Acoustic Absorption Material at Middle-High Frequencies

  • Open Access

    REVIEW

    Pharmacological methods for ovarian function and fertility preservation in women with cancer: A literature review

    ANA S. CVETANOVIC1,2,*, MATTEO LAMBERTINI3,4, KEVIN PUNIE5, GORANA G. MATOVINA BRKO6, NIKOLA D. ZIVKOVIC7,8, MAJA J. POPOVIC6,9, MARIJANA M. MILOVIC KOVACEVIC10, LAZAR S. POPOVIC6,9

    Oncology Research, Vol.32, No.8, pp. 1309-1322, 2024, DOI:10.32604/or.2024.049743

    Abstract Oncofertility is an extremely significant topic that is increasingly being discussed owing to increased evidence indicating that fertility preservation does not affect the treatment outcomes of patients with cancer but significantly contributes to preserving life quality. The effect of chemotherapy can range from minimal effects to complete ovarian atrophy. Limited data are available on the effects of monoclonal antibodies and targeted therapies on the ovaries and fertility. Temporary ovarian suppression by administering a gonadotropin-releasing hormone agonist (GnRHa) during chemotherapy decreases the gonadotoxic effect of chemotherapy, thereby diminishing the chance of developing premature ovarian insufficiency (POI).… More > Graphic Abstract

    Pharmacological methods for ovarian function and fertility preservation in women with cancer: A literature review

  • Open Access

    ARTICLE

    A Numerical Investigation of the Effect of Boundary Conditions on Acoustic Pressure Distribution in a Sonochemical Reactor Chamber

    Ivan Sboev1,*, Tatyana Lyubimova2,3, Konstantin Rybkin3, Michael Kuchinskiy2,3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1425-1439, 2024, DOI:10.32604/fdmp.2024.051341

    Abstract The intensification of physicochemical processes in the sonochemical reactor chamber is widely used in problems of synthesis, extraction and separation. One of the most important mechanisms at play in such processes is the acoustic cavitation due to the non-uniform distribution of acoustic pressure in the chamber. Cavitation has a strong impact on the surface degradation mechanisms. In this work, a numerical calculation of the acoustic pressure distribution inside the reactor chamber was performed using COMSOL Multiphysics. The numerical results have revealed the dependence of the structure of the acoustic pressure field on the boundary conditions More > Graphic Abstract

    A Numerical Investigation of the Effect of Boundary Conditions on Acoustic Pressure Distribution in a Sonochemical Reactor Chamber

  • Open Access

    ARTICLE

    Effects of Temperature and Liquid Nitrogen (LN2) on Coal’s Mechanical and Acoustic Emission (AE) Properties

    Teng Teng1,2, Yuhe Cai3, Linchao Wang3,*, Yanzhao Zhu2

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1181-1202, 2024, DOI:10.32604/fdmp.2023.044532

    Abstract Liquid nitrogen has shown excellent performances as a good fracturing medium in the extraction of unconventional natural gas, and its application in coalbed methane extraction is currently a research hotspot. This study focuses on the acoustic emission properties of coal specimens treated utilizing liquid nitrogen with varying initial temperatures in a three-point bending environment. Through examination of the load-displacement curves of the considered coal samples, their mechanical properties are also revealed for different initial temperatures and cycling frequencies. The findings demonstrate a gradual decline in the maximum load capacity of coal rock as the temperature… More >

  • Open Access

    ARTICLE

    Knockdown of Long Noncoding RNA uc.338 by siRNA Inhibits Cellular Migration and Invasion in Human Lung Cancer Cells

    Xuexin Gao*, Xuezhen Gao, Chao Li*, Yukun Zhang*, Lei Gao

    Oncology Research, Vol.24, No.5, pp. 337-343, 2016, DOI:10.3727/096504016X14666990347671

    Abstract Lung cancer remains a critical health concern worldwide. Long noncoding RNAs with ultraconserved elements have recently been implicated in human tumorigenesis. The present study investigated the role of ultraconserved element 338 (uc.338) in the regulation of cell proliferation and metastasis in human lung cancer. Our data showed that the expression of uc.338 in lung cancer was remarkably increased in vivo and in vitro. Depletion of uc.338 with specific siRNA interference retarded the cell proliferative rate in lung cancer cell lines NCI-H929 and H1688. Furthermore, knockdown of uc.338 caused cell cycle arrest in the G0/G1 phase in More >

  • Open Access

    ARTICLE

    Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor

    Dina Polosukhina*, Harold D. Love*†, Harold L. Moses‡§¶#, Ethan Lee**††, Roy Zent†§**‡‡, Peter E. Clark*‡

    Oncology Research, Vol.25, No.9, pp. 1653-1664, 2017, DOI:10.3727/096504017X14992942781895

    Abstract Wilms tumor (WT) is the most common renal malignancy in children and the fourth most common pediatric solid malignancy in the US. Although the mechanisms underlying the WT biology are complex, these tumors most often demonstrate activation of the canonical Wnt/β-catenin pathway. We and others have shown that constitutive activation of β-catenin restricted to the renal epithelium is sufficient to induce primitive renal epithelial tumors, which resemble human WT. Here we demonstrate that pharmacologic inhibition of β-catenin gene transcription with pyrvinium inhibits tumor growth and metastatic progression in a murine model of WT. Cellular invasion More >

  • Open Access

    ARTICLE

    Generalized nth-Order Perturbation Method Based on Loop Subdivision Surface Boundary Element Method for Three-Dimensional Broadband Structural Acoustic Uncertainty Analysis

    Ruijin Huo1,2,3, Qingxiang Pei1,2,3, Xiaohui Yuan1,*, Yanming Xu3

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 2053-2077, 2024, DOI:10.32604/cmes.2024.049185

    Abstract In this paper, a generalized th-order perturbation method based on the isogeometric boundary element method is proposed for the uncertainty analysis of broadband structural acoustic scattering problems. The Burton-Miller method is employed to solve the problem of non-unique solutions that may be encountered in the external acoustic field, and the th-order discretization formulation of the boundary integral equation is derived. In addition, the computation of loop subdivision surfaces and the subdivision rules are introduced. In order to confirm the effectiveness of the algorithm, the computed results are contrasted and analyzed with the results under Monte More >

  • Open Access

    REVIEW

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

    VIRAAJ VISHNU PRASAD, JENNIFER SALLY SAMSON, VENKATACHALAM DEEPA PARVATHI*

    BIOCELL, Vol.48, No.5, pp. 693-706, 2024, DOI:10.32604/biocell.2024.048776

    Abstract Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an individual. In addition to aiding the regulation of aerobic and anaerobic metabolism, exercise can stimulate the synthesis of exerkine hormones in the circulatory system. Among several exerkines that have been investigated for their therapeutic potential, Brain-derived neurotrophic factor (BDNF) is considered the most promising candidate, especially in the management of neurodegenerative diseases. Owing to the ability of physical activity to enhance BDNF synthesis, several experimental studies conducted so far have validated this hypothesis and produced satisfactory results at More > Graphic Abstract

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

  • Open Access

    ARTICLE

    Study of Optical, Electrical and Acoustical Properties of CuSO4 Doped Polyvinyl Pyrrolidone (PVP) based Polymer Solutions

    RAJEEV KUMAR

    Journal of Polymer Materials, Vol.37, No.3-4, pp. 131-142, 2020, DOI:10.32381/JPM.2020.37.3-4.2

    Abstract The optical, electrical and acoustical properties of a polymer solution based on polyvinyl pyrrolidone (PVP) doped with different concentration of cupric sulphate (CuSO4 ) were studied.UVVIS spectroscopy results reflected that absorption increases in asymmetric manner and the absorption peak showed red shift with increasing Cu ions concentration. The optical band gap (direct and indirect) was found to decrease with increase in Cu ions concentration in the polymer due to increase in the density of localized states in the band-gap.The value of Urbach energy is also evaluated from the transmission spectra and the activation energies are also More >

  • Open Access

    ARTICLE

    Tensile Failure Characterization of Glass/Epoxy Composites using Acoustic Emission RMS Data

    K. KRISHNAMOORTHYa,*, N. PRABHUb

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 215-226, 2023, DOI:10.32381/JPM.2023.40.3-4.7

    Abstract The acoustic emission monitoring with artificial neural networks predicts the ultimate strength of glass/epoxy composite laminates using Acoustic Emission Data. The ultimate loads of all the specimens were used to characterise the emission of hits during failure modes. The six layered glass fiber laminates were prepared (in woven mat form) with epoxy as the binding medium by hand lay-up technique. At room temperature, with a pressure of 30 kg/cm2, the laminates were cured. The laminates of standard dimensions as per ASTM D3039 for the tensile test were cut from the lamina. The Acoustic Emission (AE) test More >

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