Nurhadi, Rabiah Abdul Kadir^*, Ely Salwana Mat Surin, Mahidur R. Sarker^*

Computer Systems Science and Engineering, Vol.48, No.6, pp. 1405-1435, 2024, DOI:10.32604/csse.2024.051851 - 22 November 2024

Abstract A data lake (DL), abbreviated as DL, denotes a vast reservoir or repository of data. It accumulates substantial volumes of data and employs advanced analytics to correlate data from diverse origins containing various forms of semi-structured, structured, and unstructured information. These systems use a flat architecture and run different types of data analytics. NoSQL databases are nontabular and store data in a different manner than the relational table. NoSQL databases come in various forms, including key-value pairs, documents, wide columns, and graphs, each based on its data model. They offer simpler scalability and generally outperform… More >

YUAN YIN¹, ZHENGYIN WANG¹, YUJIE HU¹, JIA WANG¹, YI WANG^2,*, QUN LU^1,*

Oncology Research, Vol.32, No.12, pp. 1881-1890, 2024, DOI:10.32604/or.2024.048007 - 13 November 2024

Abstract Background: Caffeic acid (CA) is considered a promising phytochemical that has inhibited numerous cancer cell proliferation. Therefore, it is gaining increasing attention due to its safe and pharmacological applications. In this study, we investigated the role of CA in inhibiting the Interleukin-6 (IL-6)/Janus kinase (JAK)/Signal transducer and activator of transcription-3 (STAT-3) mediated suppression of the proliferation signaling in human prostate cancer cells. Materials and Methods: The role of CA in proliferation and colony formation abilities was studied using 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay and colony formation assays. Tumour cell death and cell cycle arrest were… More >

TIANYUN HAN^#, ZHONG LI^#, LUONING ZHANG, LINSHEN XIE^*

BIOCELL, Vol.48, No.11, pp. 1625-1638, 2024, DOI:10.32604/biocell.2024.055029 - 07 November 2024

Abstract Objective: The study aimed to explore the protective mechanism of Ganoderic acid A (GAA) in renal fibrosis and to verify that GAA can ameliorate renal fibrosis by regulating the Niemann-pick C1-like 1 (NPC1L1) gene. Methods: Transforming growth factor beta1 (TGF-β1) was used to treat Human Kidney-2 (HK-2) cells to establish a renal fibrosis model. The differentially expressed genes in the control (CTRL) group, TGF-β1 group, and TGF-β1 + GAA group were screened via transcriptome sequencing technology and verified by qPCR and Western blot experiments. The NPC1L1 gene overexpression plasmid was constructed. The expression levels of N-cad, E-cad,… More >

BINGJIE LIN¹, XIAOBO YING², CHUANLING ZHANG^3,*, GUOJUN ZHANG^1,*

BIOCELL, Vol.48, No.11, pp. 1613-1623, 2024, DOI:10.32604/biocell.2024.053652 - 07 November 2024

Abstract Objectives: This study explores the protective effects of glycyrrhizic acid (GA) on sepsis-induced cellular damage and inflammation in acute lung injury (ALI), specifically through the modulation of the sirtuin 1 (SIRT1) and high mobility group box 1 (HMGB1) pathway. Methods: The study employed two experimental models: lipopolysaccharide (LPS)-induced BEAS-2B human lung epithelial cells and cecal ligation and puncture (CLP) rats, to simulate sepsis conditions. The cell model involved treatments with LPS, GA, control siRNA (si-NC), and SIRT1-specific siRNA (si-SIRT1). Evaluations included cell viability, apoptosis, and cytokine production. In the rat model, treatments included GA and… More >

Catalina Vargas-Acevedo¹, Gareth J. Morgan¹, Rhynn Soderstrom², Richard Ing³, Nicholas Houska³, Jenny E. Zablah^1,*

Congenital Heart Disease, Vol.19, No.4, pp. 389-397, 2024, DOI:10.32604/chd.2024.055121 - 31 October 2024

Abstract Introduction: Pulmonary hemorrhage (PHm) is a life-threatening complication that can occur after catheter-based interventions in patients with pulmonary vein stenosis (PVS). Inhaled racemic epinephrine (iRE) and tranexamic acid (iTXA) have been used in other conditions, but a standardized approach in PVS has not been described. We aimed to describe the current management of PHm after PVS catheter-based interventions. Methods: We present a retrospective review of episodes of PHm from July 2022 to February 2024. PHm was defined as frank blood suctioned from the endotracheal tube including blood-tinged secretions and >3% decrease in saturations and/or ventilatory… More >

Lilik Astari^1,2,*, Benoit Belleville¹, Kenji Umemura³, Alex Filkov⁴, Barbara Ozarska¹, Robert H. Crawford⁵

Journal of Renewable Materials, Vol.12, No.10, pp. 1729-1756, 2024, DOI:10.32604/jrm.2024.054786 - 23 October 2024

Abstract The demand for particleboard is increasing along with economic and population growth. However, two major barriers to the manufacture of particleboard are a shortage of raw materials (woodchips) and the emission of formaldehyde from conventional adhesives. Agricultural by-products such as corn stalks contain an abundance of renewable lignocellulosic fiber. This study evaluates the effect of citric acid as a natural adhesive and fire retardant addition on the physical, mechanical, and fire retardancy properties of particleboards fabricated from corn stalks. A cost-effective and inorganic salt, calcium carbonate, was tested to enhance the fire retardancy. Ammonium dihydrogen… More > Graphic Abstract

Denis Miroshnichenko¹, Vladimir Lebedev², Katerina Lebedeva², Аnna Cherkashina², Sergey Petrushenko^3,4,*, Olena Bogoyavlenska¹, Аnzhela Olkhovska⁵, Ihor Hrubnyk⁶, Liudmyla Maloshtan⁶, Natalja Klochko⁷

Journal of Renewable Materials, Vol.12, No.10, pp. 1691-1713, 2024, DOI:10.32604/jrm.2024.054769 - 23 October 2024

Abstract The main goal of the article is the creation and study of thermosensitive and wound-healing gelatin-alginate biopolymer hydrogels modified with humic acids. Their rheological properties, swelling and contraction behavior were experimentally investigated, elucidated using Fourier transform infrared spectroscopy and used to achieve the physiological melting point, which is necessary for successful drug delivery. It has been shown that in the gelatin-alginate-humic acid biopolymer hydrogels systems, it is possible to obtain a gel-sol transition temperature close to the physiological temperature of 37°C, which is important for drug delivery in the treatment of wounds. By changing the… More >

Manivasagam Vishwa Rohini^1,#, Sathish Kiruba¹, Danniel Santhanaraj¹, Prakash Priyanka Nair¹, P. Sudhakara^2,*, Jujhar Singh³, Balamurugan Rathinam^4,*, Vanaraj Ramkumar^5,6,#

Journal of Polymer Materials, Vol.41, No.3, pp. 159-178, 2024, DOI:10.32604/jpm.2024.054801 - 30 September 2024

Abstract The Cavendish banana, Musa acuminata, is a climacteric fruit that ripens quickly after harvest. Due to their high perishability and susceptibility to disease, bananas have substantial postharvest losses. After harvesting, it is important to extend the bananas’ shelf life. Unique coating gel solutions based on glycerol and ascorbic acid were developed to accomplish this. Chitosan mixed with glacial acetic acid, lactic acid, and sodium alginate were among the gel solutions in these combinations. The goal was to improve banana preservation while maintaining freshness and quality by implementing innovative formulations and techniques. The fruits are hand-dried and… More >

Shahin Imran^1,2,*, Md. Asif Mahamud³, Newton Chandra Paul¹, Prosenjit Sarker⁴, Md. Tahjib-Ul-Arif⁵, Nazmul Islam⁵, Mohammad Saidur Rhaman⁶, Saleh H. Salmen⁷, Sulaiman Ali Alharbi⁷, Mohammad Javed Ansari⁸, Mohammed Ali Alshehri⁹, Akbar Hossain^10,*

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2251-2266, 2024, DOI:10.32604/phyton.2024.055736 - 30 September 2024

Abstract Soybean (Glycine max) is a potential legume crop, but it cannot thrive in mild salinity. Salicylic acid (SA) is a renowned plant growth hormone that improves tolerance to saline conditions. Hence, the study was performed to understand the functions of priming seeds and supplementation of SA in modulating salt tolerance in soybean seedlings. When exposed to salt stress, soybean seedlings showed considerably higher contents of hydrogen peroxide (H₂O₂) and malondialdehyde (MDA) while having decreased germination and growth factors, water contents, and photosynthetic pigments. The germination rate, final germination percentage, germination index, germination energy, and seed vigor index… More >

Dongxue Su¹, Jiarui Zheng¹, Yuwei Yi¹, Shuyuan Zhang¹, Luxin Feng¹, Danzeng Quzhen², De Qiong³, Weiwei Zhang¹, Qijian Wang¹, Feng Xu^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2317-2337, 2024, DOI:10.32604/phyton.2024.055350 - 30 September 2024

Abstract The multifaceted roles of MYB transcriptional regulators are pivotal in orchestrating the complex processes of secondary metabolism, stress tolerance mechanisms, and life cycle progression and development. This study extensively examined the JrMYB genes using whole genome and transcriptomic data, focusing on identifying putative MYB genes associated with fatty acid metabolism. 126 MYB genes were identified within the walnut genome, characterized by hydrophilic proteins spanning lengths ranging from 78 to 1890 base pairs. Analysis of cis-acting elements within the promoter regions of MYB genes revealed many elements linked to cell development, environmental stress, and phytohormones. Transcriptomic data was utilized… More > Graphic Abstract