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  • Open Access

    ARTICLE

    An Assisted Diagnosis of Alzheimer’s Disease Incorporating Attention Mechanisms Med-3D Transfer Modeling

    Yanmei Li1,*, Jinghong Tang1, Weiwu Ding1, Jian Luo2, Naveed Ahmad3, Rajesh Kumar4

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 713-733, 2024, DOI:10.32604/cmc.2023.046872

    Abstract Alzheimer’s disease (AD) is a complex, progressive neurodegenerative disorder. The subtle and insidious onset of its pathogenesis makes early detection of a formidable challenge in both contemporary neuroscience and clinical practice. In this study, we introduce an advanced diagnostic methodology rooted in the Med-3D transfer model and enhanced with an attention mechanism. We aim to improve the precision of AD diagnosis and facilitate its early identification. Initially, we employ a spatial normalization technique to address challenges like clarity degradation and unsaturation, which are commonly observed in imaging datasets. Subsequently, an attention mechanism is incorporated to selectively focus on the salient… More >

  • Open Access

    ARTICLE

    Large-Scale 3D Thermal Transfer Analysis with 1D Model of Piped Cooling Water

    Shigeki Kaneko1, Naoto Mitsume2, Shinobu Yoshimura1,*

    Digital Engineering and Digital Twin, Vol.2, pp. 33-48, 2024, DOI:10.32604/dedt.2023.044279

    Abstract In an integrated coal gasification combined cycle plant, cooling pipes are installed in the gasifier reactor and water cooling is executed to avoid reaching an excessively high temperature. To accelerate the design, it is necessary to develop an analysis system that can simulate the cooling operation within the practical computational time. In the present study, we assumed the temperature fields of the cooled object and the cooling water to be governed by the three-dimensional (3D) heat equation and the one-dimensional (1D) convection-diffusion equation, respectively. Although some existing studies have employed similar modeling, the applications have been limited to simple-shaped structures.… More >

  • Open Access

    ARTICLE

    Finite Element Simulation Analysis of a Novel 3D-FRSPA for Crawling Locomotion

    Bingzhu Wang1,*, Xiangrui Ye2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1401-1425, 2024, DOI:10.32604/cmes.2024.047364

    Abstract A novel three-dimensional-fiber reinforced soft pneumatic actuator (3D-FRSPA) inspired by crab claw and human hand structure that can bend and deform independently in each segment is proposed. It has an omni-directional bending configuration, and the fibers twined symmetrically on both sides to improve the bending performance of FRSPA. In this paper, the static and kinematic analysis of 3D-FRSPA are carried out in detail. The effects of fiber, pneumatic chamber and segment length, and circular air chamber radius of 3D-FRSPA on the mechanical performance of the actuator are discussed, respectively. The soft mobile robot composed of 3D-FRSPA has the ability to… More >

  • Open Access

    ARTICLE

    Advancing Wound Filling Extraction on 3D Faces: An Auto-Segmentation and Wound Face Regeneration Approach

    Duong Q. Nguyen1, Thinh D. Le3, Phuong D. Nguyen3, Nga T. K. Le2, H. Nguyen-Xuan3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 2197-2214, 2024, DOI:10.32604/cmes.2023.043992

    Abstract Facial wound segmentation plays a crucial role in preoperative planning and optimizing patient outcomes in various medical applications. In this paper, we propose an efficient approach for automating 3D facial wound segmentation using a two-stream graph convolutional network. Our method leverages the Cir3D-FaIR dataset and addresses the challenge of data imbalance through extensive experimentation with different loss functions. To achieve accurate segmentation, we conducted thorough experiments and selected a high-performing model from the trained models. The selected model demonstrates exceptional segmentation performance for complex 3D facial wounds. Furthermore, based on the segmentation model, we propose an improved approach for extracting… More > Graphic Abstract

    Advancing Wound Filling Extraction on 3D Faces: An Auto-Segmentation and Wound Face Regeneration Approach

  • Open Access

    ARTICLE

    Low-molecular-weight fucoidan inhibits the proliferation of melanoma via Bcl-2 phosphorylation and PTEN/AKT pathway

    MINJI PARK1, CHULHWAN BANG2, WON-SOO YUN3, YUN-MI JEONG3,*

    Oncology Research, Vol.32, No.2, pp. 273-282, 2024, DOI:10.32604/or.2023.044362

    Abstract Fucoidan, a sulfate polysaccharide obtained from brown seaweed, has various bioactive properties, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidant, anti-coagulant, anti-thrombotic, anti-angiogenic, and anti-Helicobacter pylori properties. However, the effects of low-molecular-weight fucoidan (LMW-F) on melanoma cell lines and three dimensional (3D) cell culture models are not well understood. This study aimed to investigate the effects of LMW-F on A375 human melanoma cells and cryopreserved biospecimens derived from patients with advanced melanoma. Ultrasonic wave was used to fragment fucoidan derived from Fucus vesiculosus into smaller LMW-F. MTT and live/dead assays showed that LMW-F inhibited cell proliferation in both A375 cells and patient-derived melanoma… More >

  • Open Access

    ARTICLE

    Advancing Brain Tumor Analysis through Dynamic Hierarchical Attention for Improved Segmentation and Survival Prognosis

    S. Kannan1,*, S. Anusuya2

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3835-3851, 2023, DOI:10.32604/cmc.2023.042465

    Abstract Gliomas, the most prevalent primary brain tumors, require accurate segmentation for diagnosis and risk assessment. In this paper, we develop a novel deep learning-based method, the Dynamic Hierarchical Attention for Improved Segmentation and Survival Prognosis (DHA-ISSP) model. The DHA-ISSP model combines a three-band 3D convolutional neural network (CNN) U-Net architecture with dynamic hierarchical attention mechanisms, enabling precise tumor segmentation and survival prediction. The DHA-ISSP model captures fine-grained details and contextual information by leveraging attention mechanisms at multiple levels, enhancing segmentation accuracy. By achieving remarkable results, our approach surpasses 369 competing teams in the 2020 Multimodal Brain Tumor Segmentation Challenge. With… More >

  • Open Access

    ARTICLE

    An Effective Meshless Approach for Inverse Cauchy Problems in 2D and 3D Electroelastic Piezoelectric Structures

    Ziqiang Bai1, Wenzhen Qu2,*, Guanghua Wu3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2955-2972, 2024, DOI:10.32604/cmes.2023.031474

    Abstract In the past decade, notable progress has been achieved in the development of the generalized finite difference method (GFDM). The underlying principle of GFDM involves dividing the domain into multiple sub-domains. Within each sub-domain, explicit formulas for the necessary partial derivatives of the partial differential equations (PDEs) can be obtained through the application of Taylor series expansion and moving-least square approximation methods. Consequently, the method generates a sparse coefficient matrix, exhibiting a banded structure, making it highly advantageous for large-scale engineering computations. In this study, we present the application of the GFDM to numerically solve inverse Cauchy problems in two-… More >

  • Open Access

    ARTICLE

    Numerical Study of the Biomechanical Behavior of a 3D Printed Polymer Esophageal Stent in the Esophagus by BP Neural Network Algorithm

    Guilin Wu1,2, Shenghua Huang1, Tingting Liu3, Zhuoni Yang3, Yuesong Wu2, Guihong Wei1, Peng Yu1,*, Qilin Zhang4, Jun Feng4, Bo Zeng5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2709-2725, 2024, DOI:10.32604/cmes.2023.031399

    Abstract Esophageal disease is a common disorder of the digestive system that can severely affect the quality of life and prognosis of patients. Esophageal stenting is an effective treatment that has been widely used in clinical practice. However, esophageal stents of different types and parameters have varying adaptability and effectiveness for patients, and they need to be individually selected according to the patient’s specific situation. The purpose of this study was to provide a reference for clinical doctors to choose suitable esophageal stents. We used 3D printing technology to fabricate esophageal stents with different ratios of thermoplastic polyurethane (TPU)/(Poly-ε-caprolactone) PCL polymer,… More >

  • Open Access

    ARTICLE

    3D NUMERICAL ANALYSIS ON FLOW CONFIGURATIONS AND HEAT TRANSFER CHARACTERISTICS FOR FIN-AND-OVAL-TUBE HEAT EXCHANGER WITH V-DOWNSTREAM DELTA WINGLET VORTEX GENERATORS

    Amnart Boonloia, Withada Jedasadaratanachaib,*

    Frontiers in Heat and Mass Transfer, Vol.5, pp. 1-15, 2014, DOI:10.5098/hmt.5.19

    Abstract 3D numerical investigations for heat transfer characteristics and flow configurations in a fin–and-oval-tube heat exchanger with V-tip pointing downstream delta winglet pairs (DDWP) are examined. The DDWPs are placed on the fin surface with pointing downstream and the oval tube row number is set at three in a staggered arrangement. The flow attack angles (θ = 15°, 30°, 45° and 60°) and the distance from V-tip to the oval tube center in transverse axis (a = 3.77, 4.77 and 5.77 mm) are investigated for Reynolds number based on hydraulic diameter, Re = 500 – 2500. The numerical results are compared… More >

  • Open Access

    ARTICLE

    Effect of the Wick Deflection Angles on Heat Transfer Characteristics for the Flat LHP

    Zhuohuan Hu1, Sixian Sun1, Chengwei Yuan1, Yan Cao2, Jiayin Xu1,*

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 107-123, 2023, DOI:10.32604/fhmt.2023.041837

    Abstract Loop Heat Pipe (LHP) is an efficient two-phase heat transfer device, which can be used in waste heat recovery, electronics cooling, aerospace and other fields. The wick, the core component of LHP, plays an important role in its start-up and operation. In this paper, the wick fabricated by 3D printing technology had uniform and interconnected pores. In the experiment, the position of the parallel vapor removal grooves was always fixed towards the vapor outlet. When the cylindrical wick was placed in the evaporator, the rotation angle relative to its central axis could be changed, thus changing the number and shape… More > Graphic Abstract

    Effect of the Wick Deflection Angles on Heat Transfer Characteristics for the Flat LHP

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