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    ARTICLE

    Edematogenic and myotoxic activities of the duvernoy’s gland secretion of Philodryas olfersii from the north-east region of Argentina

    OFELIA ACOSTA DE PÉREZ1, LAURA LEIVA DE VILA2, MARÍA ELISA PEICHOTO2, SILVANA MARUÑAK3, RAQUEL RUÍZ3, PAMELA TEIBLER3, CAROLINA GAY2, LAURA REY4

    BIOCELL, Vol.27, No.3, pp. 363-370, 2003, DOI:10.32604/biocell.2003.27.363

    Abstract Philodryas olfersii is found in South America, from Amazonas to Patagonia. It is important to characterize the venom of P. olfersii, who inhabits the North-East region of Argentina, since snake venoms are known to exhibit considerable variability in composition and biological activities. In this work, mice weighing 18-20 g (n = 4 for each experimental group) were used. For the edematogenic activity mice were injected s.c. in the right foot pad with 50 µl of solutions containing different amounts of venom, whereas the left foot pad was injected with 50 µl of PBS. Two hours after injection mice… More >

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