Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (1)
  • Open Access

    ABSTRACT

    Modeling Mechano-chemical Couplings in Bone Adaptation by Remodeling

    Taiji Adachi1,*, Yoshitaka Kameo1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 88-88, 2019, DOI:10.32604/mcb.2019.07417

    Abstract Bone adaptation by remodeling is a process to change its outer shape and internal structure to the changing mechanical environment by osteoclastic bone resorption and osteoblastic bone formation. These cellular activities are regulated by mechanosensory network of osteocytes embedded in bone matrix. An imbalance between bone resorption and formation due to low loadings or disuse results in metabolic bone disorders such as osteoporosis. Many studies have identified various signaling pathways that regulate these cellular activities; however, the physiological and pathological conditions of bone as a system remain difficult to understand because of the complexity of… More >

Displaying 1-10 on page 1 of 1. Per Page