Open Access

MINI REVIEW

Therapeutic Potential of the Medicinal Plant Tinospora cordifolia–Minireview

by Lohanathan Bharathi Priya^1,#, Balamuralikrishnan Balasubramanian^2,#, Balamurugan Shanmugaraj³, Shanmugam Subbiah⁴, Rouh-Mei Hu⁵, Chih-Yang Huang^6,7,8,9,*, Rathinasamy Baskaran^5,*

1 Integrative Stem Cell Center, China Medical University Hospital, Taichung, 40432, Taiwan
2 Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, 05006, South Korea
3 Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10100, Thailand
4 Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 641046, India
5 Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan
6 Centre of General Education, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien, 97004, Taiwan
7 Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien, 97004, Taiwan
8 Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40432, Taiwan
9 Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, 41354, Taiwan

* Corresponding Authors: Chih-Yang Huang. Email: ; Rathinasamy Baskaran. Email:
# These authors contributed equally to this work as the first author

Phyton-International Journal of Experimental Botany 2022, 91(6), 1129-1140. https://doi.org/10.32604/phyton.2022.017707

Received 31 May 2021; Accepted 06 December 2021; Issue published 14 February 2022

Abstract

For thousands of years, plant based herbal medicines have been utilized by millions of people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as the Chinese, African and Indian medical systems, like Siddha, Ayurveda, Unani, and Homeopathy. Tinospora cordifolia (TC) is a medicinal plant belonging to the family Menispermaceae. It is a big deciduous, climbing shrub growing prevalently in the tropical part of Indian subcontinent regions such as India, Pakistan, Nepal, Bhutan, Bangladesh and Srilanka, and in Myanmar, and China. Guduchi, Giloy, Shindilkodi, and Amritha are all the common names for this plant. Extracts from different parts of this herbal plant have been used to treat many diseases. In Ayurvedic medicine, extract from this plant is used for preparing “rasayanas”, which is known to cure diabetes, skin diseases, allergic conditions, jaundice, cardiovascular diseases, rheumatoid arthritis, poisoning, and microbial infections. T. cordifolia has a many bioactive phytochemicals that have been isolated from its aerial parts and roots. Many bioactive principles have been reported from this plant which belong to various classes like alkaloids, aliphatic compounds, diterpenoid lactones, phenolics, flavonoids, glycosides, sesquiterpenoids, lignans, steroids and polysaccharides. T. cordifolia possesses medicinal properties such as antioxidant, antiallergic, antiinflammatory, antimicrobial, antiviral, antidote, antitumor, antileprotic, antispasmodic, and antidiabetic properties. The present review will provide a comprehensive therapeutic potential of T. cordifolia.

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