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Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes
Jaswinder Kaur1, Manish Vyas2, Joginder Singh1, Ram Prasad3,*, Jeena Gupta1,*
1 School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, 144411, India
2 School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India
3 Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, 845801, India
* Corresponding Authors: Ram Prasad. Email: ; Jeena Gupta. Email: ;
(This article belongs to the Special Issue: Plant Secondary Metabolites: Recent Advances and Opportunities)
Phyton-International Journal of Experimental Botany 2020, 89(4), 795-803. https://doi.org/10.32604/phyton.2020.09420
Received 12 December 2019; Accepted 02 February 2020; Issue published 09 November 2020
Abstract
In recent years, there has been an increase in epidemiological studies to
highlight the health benefits of plant secondary metabolites. Flavonoids (polyphenolic plant secondary metabolites) are recently emerging as an important source
for the discovery of new drugs increasing their pharmaceuticals, nutraceutical
and medicinal applications. Naringenin is a flavanone, enriched in citrus fruits,
tomatoes, bergamot, etc. which has been evaluated extensively for managing
diabetes. However, in addition to this, naringenin had been ascribed to various important biological activities like antioxidant, antiviral, anticancer, anti-inflammatory,
antiestrogenic, etc. This article aims at highlighting the therapeutic value of
naringenin in managing disorders other than diabetes and its role in regulating
gene expression by altering chromatin structure as histone deacetylase inhibitor.
The understanding of these phenomena will increase the overall knowledge of
the various health-promoting effects of citrus fruits.
Keywords
Cite This Article
APA Style
Kaur, J., Vyas, M., Singh, J., Prasad, R., Gupta, J. (2020). Therapeutic applications of naringenin, a flavanone enriched in citrus fruits, for disorders beyond diabetes. Phyton-International Journal of Experimental Botany, 89(4), 795-803. https://doi.org/10.32604/phyton.2020.09420
Vancouver Style
Kaur J, Vyas M, Singh J, Prasad R, Gupta J. Therapeutic applications of naringenin, a flavanone enriched in citrus fruits, for disorders beyond diabetes. Phyton-Int J Exp Bot. 2020;89(4):795-803 https://doi.org/10.32604/phyton.2020.09420
IEEE Style
J. Kaur, M. Vyas, J. Singh, R. Prasad, and J. Gupta "Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes," Phyton-Int. J. Exp. Bot., vol. 89, no. 4, pp. 795-803. 2020. https://doi.org/10.32604/phyton.2020.09420
Citations