Special Issues

Advances in Molecular Insights of Plant Secondary Metabolites: Biosynthesis, Regulation, and Applications

Submission Deadline: 31 December 2025 View: 72 Submit to Special Issue

Guest Editors

Prof. Dr. Marcello Iriti 

Email: marcello.iriti@unimi.it

Affiliation: Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

Homepage:

Research Interests: phytotherapeutics; essential oils; bioactive phytochemicals; ethnobotany; ethnopharmacology; antimicrobial resistance; one health; food security

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Summary

The "Advances in Molecular Insights of Plant Secondary Metabolites: Biosynthesis, Regulation, and Applications" special issue explores the latest developments in plant secondary metabolism, emphasizing the molecular mechanisms underlying the biosynthesis and regulation of bioactive compounds. Secondary metabolites, including alkaloids, isoprenoids, and phenylpropanoids, play crucial roles in plant defense, growth, and development, as well as in interactions with the environment. This special issue will showcase cutting-edge research on the molecular pathways, enzymatic processes, and gene regulation networks that control the synthesis of these metabolites. In addition, the problem will highlight novel biotechnological applications of plant secondary metabolites in pharmaceuticals, agrochemicals, and sustainable agriculture, as well as their potential for improving human health and ecosystem sustainability.Potential topics include, but are not limited to:

1. Plant resistance mechanisms against pathogens and pests;

2. Plant tolerance strategies against abiotic stresses;

3. Global climate change;

4. Water, air and soil pollution;

5. Medicinal plants and their biological activities;

6. Essential oils and their applications;

7. Advances in omics technologies (e.g., genomics, transcriptomics, metabolomics) in secondary metabolism research.


Keywords

plant secondary metabolites; biosynthesis; gene regulation; metabolic pathways; alkaloids; phenylpropanoids; phenolics; flavonoids; isoprenoids; terpenoids; metabolic engineering; biotechnological applications; omics technologies; plant-environment interactions; sustainable agriculture; bioactive secondary metabolites

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