Special Issues

Advances in Molecular Insights of Plant Secondary Metabolites: Biosynthesis, Regulation, and Applications

Submission Deadline: 31 December 2025 View: 191 Submit to Special Issue

Guest Editors

Prof. Dr. Marcello Iriti 

Email: marcello.iriti@unimi.it

Affiliation: Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

Homepage:

Research Interests: phytotherapeutics; essential oils; bioactive phytochemicals; ethnobotany; ethnopharmacology; antimicrobial resistance; one health; food security

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Summary

The "Advances in Molecular Insights of Plant Secondary Metabolites: Biosynthesis, Regulation, and Applications" special issue explores the latest developments in plant secondary metabolism, emphasizing the molecular mechanisms underlying the biosynthesis and regulation of bioactive compounds. Secondary metabolites, including alkaloids, isoprenoids, and phenylpropanoids, play crucial roles in plant defense, growth, and development, as well as in interactions with the environment. This special issue will showcase cutting-edge research on the molecular pathways, enzymatic processes, and gene regulation networks that control the synthesis of these metabolites. In addition, the problem will highlight novel biotechnological applications of plant secondary metabolites in pharmaceuticals, agrochemicals, and sustainable agriculture, as well as their potential for improving human health and ecosystem sustainability.Potential topics include, but are not limited to:

1. Plant resistance mechanisms against pathogens and pests;

2. Plant tolerance strategies against abiotic stresses;

3. Global climate change;

4. Water, air and soil pollution;

5. Medicinal plants and their biological activities;

6. Essential oils and their applications;

7. Advances in omics technologies (e.g., genomics, transcriptomics, metabolomics) in secondary metabolism research.


Keywords

plant secondary metabolites; biosynthesis; gene regulation; metabolic pathways; alkaloids; phenylpropanoids; phenolics; flavonoids; isoprenoids; terpenoids; metabolic engineering; biotechnological applications; omics technologies; plant-environment interactions; sustainable agriculture; bioactive secondary metabolites

Published Papers


  • Open Access

    ARTICLE

    Orchestrating the Phytochemical Content and Bioactivities in the Leaf, Bark, and Fruit Extracts of Cornus capitata Wall

    Deen Bandhu Dimri, Manisha Nigam, Naresh Singh, Shilpa Semwal, Marcello Iriti, Abhay Prakash Mishra
    Phyton-International Journal of Experimental Botany, DOI:10.32604/phyton.2025.061270
    (This article belongs to the Special Issue: Advances in Molecular Insights of Plant Secondary Metabolites: Biosynthesis, Regulation, and Applications)
    Abstract Cornus capitata, commonly known as the Himalayan strawberry, is a dogwood species from the family Cornaceae. Dogwood plants have been used extensively to practice conventional medicine due to their biological activities; however, the mechanisms behind these activities, particularly in C. capitata, remain largely unexplored. This study focuses on the preliminary phytochemical screening, antioxidant activity, anti-diabetic potential, and antimicrobial profiling of different extracts (i.e., leaves, bark, and fruit) from C. capitata to evaluate its potential pharmaceutical and medicinal applications. The in-vitro antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, Ferric-reducing antioxidant power (FRAP) assay, and Superoxide Anion Scavenging assay.… More >

    Graphic Abstract

    Orchestrating the Phytochemical Content and Bioactivities in the Leaf, Bark, and Fruit Extracts of <i>Cornus capitata</i> Wall

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