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Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery

Submission Deadline: 08 December 2021 (closed)

Guest Editors

Dr. Aleksandar Ž. Kostić, University of Belgrade, Serbia

Dr. Wen-Zhi Yang, Tianjin University of Traditional Chinese Medicine, China

Summary

Plants are important source of different secondary metabolites with expressed bioactivity. These compounds can be used as specific markers in chemotaxonomy for some plant species/genus/families providing unambiguous information for botanists or chemists in order to determine or to fulfill detailed chemical profile for some endemic or well-known species. It is very common that plant bioactive compounds express antioxidant properties with good ability to quench and neutralize reactive oxygen (ROS) or nitrogen (RNS) species in cells as well as to influence on some enzyme’s activity. In that way they can provide protective and positive effects in plants as well as in human body. Because of that there is a growing interest for its application as functional food ingredients or as possible medicine for some therapeutic purposes. In addition, application of some plants in folklore medicine is widespread all around the world. Advances in analytical technology have greatly accelerated the discovery of bioactive molecules or analogs. In that sense, this Special Issue is intended to collect some recent researches regarding to these topics and to provide new data about current status of scientific knowledge.

Keywords

Secondary Metabolites; Phenolics; Carotenoids; Vitamins; Fatty Acids; Chemotaxonomy; Antioxidant Properties; Food Ingredients; Therapeutics

Published Papers

Open Access

ARTICLE

In Vitro and in Silico Insights on the Biological Activities, Phenolic Compounds Composition of Hypericum perforatum L. Hairy Root Cultures
Oliver Tusevski, Marija Todorovska, Jasmina Petreska Stanoeva, Marina Stefova, Sonja Gadzovska Simic
Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 921-941, 2023, DOI:10.32604/phyton.2023.024995
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract Three Hypericum perforatum hairy root lines (HR B, HR F and HR H) along with non-transformed roots were analyzed for phenolic compounds composition and in vitro enzyme inhibitory properties. In silico molecular modeling was performed to predict the interactions of the most representative phenolic compounds in HR clones with enzymes related to depression, neurodegeneration and diabetes. Chromatographic analyses revealed that HR clones represent an efficient source of quinic acid and hydroxybenzoic acids, epicatechin and procyanidin derivatives, quercetin and kaempferol glycosides, as well numerous xanthones. In vitro antidepressant activity of HR extracts through monoamine oxidase A (MAO-A) inhibition was attributed to… More >

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ARTICLE

Extraction, Antioxidant Activity and Identification of Flavonoids from Root Tubers of Kosteletzkya virginica
Yu Zai, Shaohua Liu
Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 225-236, 2023, DOI:10.32604/phyton.2022.022576
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract Kosteletzkya virginica (K. virginica) is used for revegetation of salt-affected coastal tidal flats and as a raw material of biodiesel. K. virginica root tuber, a biowaste with low economic value, is rich in bioactive compounds. This study aimed to extract and identify flavonoids from K. virginica root tubers. The optimal extraction conditions were 1/25 (w/v) solid/liquid ratio, 40% ethanol concentration at 40°C for 60 min. Under these conditions, 65.2 ± 3.7 mg/g total flavonoid content was extracted from the roots, which were collected from salinized soil in late autumn of the third year. Antioxidant activity was evaluated through 1,1-diphenyl-2-picrylhydrazyl, hydroxyl… More >

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ARTICLE

Metabolomics Analysis of Metabolites in Forsythia suspense Fruit Using UPLC/ESI-Q TRAP-MS/MS
Lingdi Liu, Chunxiu Wen, Wei Tian, Xiaoliang Xie, Saiqun Wen, Tao Jiang
Phyton-International Journal of Experimental Botany, Vol.91, No.10, pp. 2313-2330, 2022, DOI:10.32604/phyton.2022.020295
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract Forsythiae Fructus, the fruit of Forsythia suspense is a traditional Chinese hebal medicine that has the antiviral and antioxidant effects in China. Modern analytical chemistry studies showed that the extracts of Forsythiae Fructus contain many bioactive components, such as flavonoids, lignans, phenolic acids, and terpenoids, which can be used to anti-inflammatory and treat toxicity, tonsillitis, ulcers, pharyngitis and acute nephritis. In order to study the types and quantities of metabolites in Forsythiae Fructus, we isolated, identified and analysed metabolites between two varieties of Forsythiae Fructus using UPLC/ESI-Q TRAP-MS/MS. The results showed that a total of 407 metabolites were identified in… More >

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ARTICLE

Rapid Profiling and Characterization of the Multicomponents from the Root and Rhizome of Salvia miltiorrhiza by Ultra-High Performance Liquid Chromatography/Ion Mobility-Quadrupole Time-of-Flight Mass Spectrometry in Combination with Computational Peak Annotation Workflows
Boxue Chen, Hongda Wang, Meiyu Liu, Wandi Hu, Yuexin Qian, Jiali Wang, Jie Liu, Xue Li, Jing Wang, Wenzhi Yang
Phyton-International Journal of Experimental Botany, Vol.91, No.5, pp. 1073-1088, 2022, DOI:10.32604/phyton.2022.019399
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract Herbal components characterization represents a challenging task because of the co-existing of multiple classes of naturally occurring compounds with wide spans of polarity, molecular mass, and the ubiquitous isomerism. The root and rhizome of Salvia miltiorrhiza have been utilized as a reputable traditional Chinese medicine Salviae Miltiorrhizae Radix et Rhizoma (Dan-Shen) in the treatment of cardiovascular disease. Herein, a dimension-enhanced ultra-high performance liquid chromatography/ion mobility/quadrupole time-of-flight mass spectrometry approach in combination with intelligent peak annotation workflows was established aimed to rapidly characterize the multicomponents from S. miltiorrhiza. Due to the sufficient optimization, satisfactory chromatography separation was enabled on an HSS… More >

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ARTICLE

Dimension-Enhanced Ultra-High Performance Liquid Chromatography/Ion Mobility-Quadrupole Time-of-Flight Mass Spectrometry Combined with Intelligent Peak Annotation for the Rapid Characterization of the Multiple Components from Seeds of Descurainia sophia
Simiao Wang, Xue Li, Boxue Chen, Shitong Li, Jiali Wang, Jing Wang, Mingshuo Yang, Xiaoyan Xu, Hongda Wang, Wenzhi Yang
Phyton-International Journal of Experimental Botany, Vol.91, No.3, pp. 541-567, 2022, DOI:10.32604/phyton.2022.018571
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract The complex composition of herbal metabolites necessitates the development of powerful analytical techniques aimed to identify the bioactive components. The seeds of Descurainia sophia (SDS) are utilized in China as a cough and asthma relieving agent. Herein, a dimension-enhanced integral approach, by combining ultra-high performance liquid chromatography/ion mobility-quadrupole time-of-flight mass spectrometry (UHPLC/IM-QTOF-MS) and intelligent peak annotation, was developed to rapidly characterize the multicomponents from SDS. Good chromatographic separation was achieved within 38 min on a UPLC CSH C18 (2.1 × 100 mm, 1.7 μm) column which was eluted by 0.1% formic acid in water (water phase) and acetonitrile (organic phase).… More >

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ARTICLE

Phytochemical Analysis and Antioxidant Activity of Crocus speciosus Leaves
Olha Mykhailenko, Ivan Bezruk, Victoriia Volochai, Volodymyr Mishchenko, Liudas Ivanauskas, Victoriya Georgiyants
Phyton-International Journal of Experimental Botany, Vol.91, No.1, pp. 207-221, 2022, DOI:10.32604/phyton.2022.016458
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract The numerous studies indicate leaves of plants are a rich source of bioactive compounds that can be a valuable source of compounds used in the pharmaceutical and cosmetic industries. Aim of this study was to investigate the chemical composition and the antioxidant property of Crocus speciosus leaves. Primary phytochemical screening of C. speciosus leaves revealed the presence of some following compound categories such as phenolic compounds, aminoacids, saponins, proteins, tannins, triterpenoids, glycosides, polysaccharides. The total flavonoids and phenolic compounds content were determined spectrophotometrically and by HPLC-DAD and HPLC-MS. Antiradical activity was determined by ABTS radical-cation scavenging method, spectrophotometrically. The total… More >

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893
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ARTICLE

Diversity Analysis of Chlorophyll, Flavonoid, Anthocyanin, and Nitrogen Balance Index of Tea Based on Dualex
Yifu Liu, Jiazhen Wang, Yao Xiao, Xiongwen Shi, Yixia Zeng
Phyton-International Journal of Experimental Botany, Vol.90, No.5, pp. 1549-1558, 2021, DOI:10.32604/phyton.2021.015557
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract The chemical compositions of tea (Camellia sinensis) are affected by numerous factors, such as cultivar, climate, leaf position, and cultivation pattern. However, under the same conditions, the chemical compositions are mainly determined by varieties. Therefore, we investigated the genetic diversity of chemical compositions of tea tree resources in China to screen excellent germplasm resources. Three chemical compositions index (including chlorophyll index, flavonoid index, and anthocyanin index) and the nitrogen balance index of tea leaves were measured in 102 tea germplasms planted in Chinese Tea Plants Improved Variety Germplasm Resources Nursery (CTPIVGRN) by Dualex on April 15 2019. Results showed that… More >

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REVIEW

Carotenoids: New Applications of “Old” Pigments
Stefan M. Kolašinac, Zora P. Dajić Stevanović, Sofija N. Kilibarda, Aleksandar Ž. Kostić
Phyton-International Journal of Experimental Botany, Vol.90, No.4, pp. 1041-1062, 2021, DOI:10.32604/phyton.2021.015996
（This article belongs to this Special Issue: Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery)
Abstract Carotenoids represent a large group of mainly red, orange, and yellow natural metabolites mainly involved in regulation of many metabolic processes. Carotenoids are beneficial for human health. Current study describes the importance, chemical composition and functioning of carotenoids. It is well known that carotenoids support pigments acting in light absorbance mechanisms during photosynthesis, and are known to protect the chlorophyll molecules from oxidative stress and reactive oxygen species (ROS) damage. Carotenoids are involved in signaling processes in plants, responses to environmental stresses, pollination, germination and reproduction, and development regulation. As nutrients of strong antioxidant activity that is primarily linked to… More >

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Plant Bioactive Compounds-Chemotaxonomic Significance, Antioxidant Properties, Potential Application as Food Ingredients as well as Therapeutics, and the Analytical Technology in Their Efficient Discovery

Guest Editors

Summary

Keywords

Published Papers

View

20

Download

7

View

241

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136

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664

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245

View

736

Download

556

View

1179

Download

743

Like

1

Cited by

1

View

1178

Download

893

View

1636

Download

915

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1611

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1521

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1

Cited by

3

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