Special Issues

Phytochemical and Pharmacological Research in Medicinal Plants

Submission Deadline: 01 November 2024 (closed) View: 268

Guest Editors

Dr. Ain Raal, Institute of Pharmacy, Faculty of Medicine, University of Tartu, Estonia
Email: ain.raal@ut.ee

Dr. Oleh Koshovyi, Institute of Pharmacy, Faculty of Medicine, University of Tartu, Estonia; National University of Pharmacy, Kharkiv, Ukraine
Email: oleh.koshovyi@ut.ee

Summary

The chemical composition and pharmacological effects of medicinal plants have been studied for a long time. Despite the development of physicochemical research methods and extensive research in medicinal plants all over the world, only 10-15% of higher plant species have been thoroughly studied so far. Therefore, it is very important to intensify the research in this direction, which will help to improve the health of mankind with far-reaching consequences.


The current special issue will publish high-level scientific results of studies in phytochemistry and pharmacology of medicinal plants, plant raw materials, herbal drugs, extracts, individual plant-origin substances, and products based on them. Both phytochemical and/or pharmacological aspects must be presented in the same manuscript.


Keywords

medicinal plants, plant raw materials, herbal drugs, extracts, natural compounds, phytochemical analysis, chemical composition, pharmacological activity

Published Papers


  • Open Access

    ARTICLE

    Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells: A Metabolite and Gene Expression Study

    Fayez Althobaiti, Hadeer Darwish, Raghad Alruqayb, Saqer S. Alotaibi, Fahad E. Alharthi, Ibrahim Jafri, Sarah Awwadh Altalhi, Ghadi Alsharif, Hussam Awwadh E Althagafi, Hesham Noureldeen, Sarah Alharthi, Jawaher Albaqami, Najla Amin T. Al Kashgry, Ahmed Noureldeen
    Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 181-198, 2025, DOI:10.32604/phyton.2025.059387
    (This article belongs to the Special Issue: Phytochemical and Pharmacological Research in Medicinal Plants)
    Abstract The interest in using the Datura stramonium plant is due to its natural products, which are used in many pharmaceutical industries. The objective of the current study was to assess the therapeutic and cytotoxic effects of the D. stramonium plant on two types of human cancer cell models (MCF7 and HT29) in vitro. A soxhlet apparatus was used to obtain methanolic extract from dried plant leaves. The recovered crude, after the solvent had evaporated, was then dispersed at varied concentrations of extract 100, 50, 20, and 0.0 µg/mL and tested to see how the cells responded. Also,… More >

  • Open Access

    ARTICLE

    Inhibitory Effect of Ponkan (Citrus reticulata ‘Ponkan’) Flavonoids on Oral Ulcers through Jak2-Stat3 Signaling Pathway

    Lili Liu, Can Hu, Huilin Cheng, Chuangju Ma, Jiancheng Sun, Yunyi Chen, Manxi Wu, Han Yang, Cui Sun, Jinping Cao, Dengliang Wang, Yue Wang, Chongde Sun
    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2499-2518, 2024, DOI:10.32604/phyton.2024.054449
    (This article belongs to the Special Issue: Phytochemical and Pharmacological Research in Medicinal Plants)
    Abstract Oral ulcers, a common mucosal affliction, severely diminish patients’ quality of life due to pain and discomfort. Despite existing treatments, the frequent recurrence of oral ulcers underscores the need for more effective therapeutic options. This study aimed to investigate the inhibitory effects of Ponkan (Citrus reticulata ‘Ponkan’) extracts and their flavonoid components on oral ulcers, exploring their potential as a natural therapy. Twenty different Ponkan cultivars were selected for flavonoid extraction and analysis. Ultra-performance liquid chromatography (UPLC) and high-resolution mass spectrometry (HRMS) were utilized for substance identification, leading to the discovery of 16 flavonoid compounds. Using… More >

    Graphic Abstract

    Inhibitory Effect of Ponkan (<i>Citrus reticulata</i> ‘Ponkan’) Flavonoids on Oral Ulcers through Jak2-Stat3 Signaling Pathway

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