Thymus serpyllum L. Essential Oil: Phytochemistry and in Vitro and in Silico Screening of Its Antimicrobial, Antioxidant and Anti-Inflammatory Properties
Samiah Hamad Al-Mijalli, Hanae Naceiri Mrabti, Amine Elbouzidi, Naglaa S. Ashmawy, Amine Batbat, Emad M. Abdallah, Wafa Laaboudi, Mohammed Aladhadh, Fahad M. Alshabrmi, Sulaiman Mohammed Alnasser, Mohamed Addi, Naoufal El Hachlafi
Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 209-227, 2025, DOI:10.32604/phyton.2025.060438
(This article belongs to the Special Issue:
Biological Activities of Essential Oils)
Abstract Thymus serpyllum L., often known as wild thyme, has been used since ancient times due to its multifaceted culinary and medicinal attributes. It is usually utilized in folk medicine to manage different health issues. This work aimed to investigate the chemical composition and biological characteristics of
T. serpyllum essential oil (EO), including its antimicrobial, antioxidant, and anti-inflammatory capabilities. Moreover, we have prompted an
in-silico simulation to reveal the underlying mode of action of these properties. The chemical characterization of
T. serpyllum (EO) by Gas Chromatography-Mass Spectrometry (GC-MS) indicated sabinene (17.33%), terpinen-4-ol (11.73%), phellandral (13.18%), and thymol (10.54%) as main…
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