Open Access

ARTICLE

Trametinib boosts palbociclib’s efficacy in breast cancer via autophagy inhibition

ANGUO WU^1,#, JIAO YAN^2,3,#, TING SU^2,4, CHI FENG¹, XIN LONG^5,6, YIRU PAN¹, RUPEI YE², TIAN XIA², HANAN LONG², JIANMING WU^1,*, XIULI XIAO^2,*

1 Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation, Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica, Key Laboratory of Medical Electrophysiology of Ministry of Education, School of Pharmacy, Southwest Medical University, Luzhou, 646000, China
2 The Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China
3 The Department of Pathology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, 621000, China
4 The Department of Pathology, Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China
5 School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, China
6 School of Clinical Medical Sciences, Southwest Medical University, Luzhou, 646000, China

* Corresponding Authors: JIANMING WU. Email: ; XIULI XIAO. Email: