Open Access

ARTICLE

IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation

WEN GE^1,2,#, YA LI^1,2,#, YUTING RUAN^1,2, NINGXIA WU^1,2, PEI MA^3,4, TONGPENG XU^3,4, YONGQIAN SHU^3,4, YINGWEI WANG^1,2, WEN QIU^1,2, CHENHUI ZHAO^3,4,*

1 Department of Immunology, Nanjing Medical University, Nanjing, 210000, China
2 Key Laboratory of Immunological Environment and Disease, Nanjing Medical University, Nanjing, 210000, China
3 Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210000, China
4 Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 210000, China

* Corresponding Author: CHENHUI ZHAO. Email:
# These authors contributed equally to this work