Open Access

ARTICLE

LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway

YAN ZHUANG^1,#, CHUNLAN NING^2,3,#, PENGFEI LIU^4,#, YANPENG ZHAO⁵, YUE LI⁶, ZHENCHI MA⁶, LULING SHAN⁶, YINGZHE PIAO⁷, PENG ZHAO^6,*, XUN JIN^2,*

1 Department of Colorectal Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China
2 Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China
3 Tianjin Medical University, Tianjin, 300070, China
4 Department of Oncology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, 300120, China
5 Tianjin Marvel Medical Laboratory, Tianjin Marvelbio Technology Co., Ltd., Tianjin, 300381, China
6 Department of Gastro Colorectal Oncology, Tianjin Cancer Hospital Airport Hospital, Tianjin, 300304, China
7 Department of Neuro-Oncology and Neurosurgery, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 300060, China

* Corresponding Authors: Xun Jin, ; Peng Zhao,