Open Access

ARTICLE

cGAS regulates the DNA damage response to maintain proliferative signaling in gastric cancer cells

BIN LIU^1,2,#, HAIPENG LIU^3,#, FEIFEI REN^1,2, HANGFAN LIU¹, IHTISHAM BUKHARI¹, YUMING FU⁴, WANQING WU⁴, MINGHAI ZHAO⁵, SHAOGONG ZHU⁶, HUI MO¹, FAZHAN LI^1,2, MICHAEL B. ZHENG⁷, YOUCAI TANG^1,2, PENGYUAN ZHENG^1,2,*, YANG MI^1,2,*

1 Henan Key Laboratory of Helicobacter Pylori & Microbiota and Gastrointestinal Cancer, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
2 Academy of Medical Science, Zhengzhou University, Zhengzhou, China
3 Clinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China
4 Gastrointestinal Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
5 Department of Gastrointestinal Surgery, Henan Cancer Hospital, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China
6 Gastrointestinal Surgery, People Hospital of Zhengzhou University, Zhengzhou, China
7 Faculty of Science, School of Interdisciplinary Science, Honours Life Sciences, McMaster University, Hamilton, ON, Canada

* Corresponding Authors: Pengyuan Zheng, ; Yang Mi,
# These authors have contributed equally to this work and share the first authorship