Open Access

ARTICLE

Profilin 2 Promotes Proliferation and Metastasis of Head and Neck Cancer Cells by Regulating PI3K/AKT/b-Catenin Signaling Pathway

Kecheng Zhou^*†1, Jie Chen^*†1, Jiayu Wu^*†1, Yangxinzi Xu^‡, Qiaoyun Wu^*†, Jingjing Yue^*†, Yu Song^§, Shengcun Li^*†, Peng Zhou^¶, Wenzhan Tu^*†, Guanhu Yang^*†, Songhe Jiang^*†

* Department of Physical Medicine and Rehabilitation, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China
† Integrative and Optimized Medicine Research Center, China–USA Institute for Acupuncture and Rehabilitation, Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China
‡ Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, Manitoba, Canada
§ Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui, P.R. China
¶ Department of Anatomy, Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China