Open Access

ARTICLE

Extracellular S100A11 Plays a Critical Role in Spread of the Fibroblast Population in Pancreatic Cancers

Hitoshi Takamatsu^*1, Ken-ichi Yamamoto^*1, Nahoko Tomonobu^*, Hitoshi Murata^*, Yusuke Inoue^†, Akira Yamauchi^‡, I Wayan Sumardika^*§, Youyi Chen^*, Rie Kinoshita^*, Masahiro Yamamura^¶, Hideyo Fujiwara^#, Yosuke Mitsui^{*, **}, Kota Araki^*††, Junichiro Futami^‡‡, Ken Saito^§§, Hidekazu Iioka^§§, I Made Winarsa Ruma^§, Endy Widya Putranto^¶¶, Masahiro Nishibori^##, Eisaku Kondo^§§, Yasuhiko Yamamoto^***, Shinichi Toyooka^††, Masakiyo Sakaguchi^*

* Department of Cell Biology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
† Faculty of Science and Technology, Division of Molecular Science, Gunma University, Kiryu, Gunma, Japan
‡ Department of Biochemistry, Kawasaki Medical School, Kurashiki, Okayama, Japan
§ Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia
¶ Department of Clinical Oncology, Kawasaki Medical School, Kurashiki, Okayama, Japan
# Department of Pathology, Kawasaki Medical School, Kurashiki, Okayama, Japan
** Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
†† Department of General Thoracic Surgery and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
‡‡ Department of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan
§§ Division of Molecular and Cellular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
¶¶ Department of Pediatrics, Dr. Sardjito Hospital/Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia
## Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
*** Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan