Guest Editors
I-Ta Lee, School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan. E-mail: itlee0128@tmu.edu.tw
Thi Thuy Tien Vo, Faculty of Dentistry, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam. E-mail: vtttien@ntt.edu.vn
Summary
Signaling transduction plays a critical role in maintaining cellular equilibrium and orchestrating complex cellular responses. This special issue delves into the intricate signaling pathways involved in oral cancer, from extracellular signals to intracellular mechanisms. Recent advances have highlighted a diverse spectrum of signaling mechanisms and their precise regulation within cells. These pathways extend from the extracellular environment through the plasma membrane to various organelles, facilitating intra-organellar communication and specific cellular responses. In oral cancer, understanding the roles of cytokines, chemokines, and other signaling molecules is essential for comprehending the disease's progression and therapeutic resistance. This special issue aims to provide comprehensive insights into these signaling processes, offering potential breakthroughs in targeted therapies and personalized medicine for oral cancer. By exploring these pathways, we aim to illuminate new strategies to improve patient outcomes, enhance our understanding of cancer biology, and ultimately advance the field of oncology research.
Keywords
Oral cancer, Signaling transduction, Molecular mechanisms, Oncogenic pathways, Tumor microenvironment, Biomarkers, Targeted therapy
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