Guest Editors
Prof. Gaetano Isola
E-mail: gaetano.isola@unict.it
Affiliation: Oral Surgery and Periodontology, School of Dentistry, University of Catania, Catania, 95124, Italy
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Research Interests: Oral Cancer; Periodontal Diseases; Oral Medicine; Periodontology; Dentistry; Oral and Maxillofacial Surgery
Dr. Alessandro Polizzi
E-mail: alexpoli345@gmail.com
Affiliation: Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124, Catania, Italy
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Research Interests: Oral Cancer; Oral Pathology; Oral Medicine; Periodontology; Oral Surgery; Oral Diseases; Dental Medicine; Oral and Maxillofacial Pathology
Summary
Oral cancer is a growing global public health problem, with 354,864 new cases and 177,384 deaths a year (WHO) and represents around 90% of malignant oral neoplasms and has a 5-year survival rate of 50–60%. Oral cancer is often preceded by oral potentially malignant disorders, which include a group of mucosal lesions and conditions (e.g., leukoplakia, erythroplakia, lichen planus, or oral submucous fibrosis) whose malignant transformation risk is currently unpredictable and evaluated according to the presence and severity of epithelial dysplasia.Although the oral cavity is easily accessible for clinical examinations, oral cancer is frequently diagnosed at a late stage, with poor prognosis and a lower quality of life for patients. Tobacco, alcohol, and human papillomavirus infection are currently considered the most important risk factors for oral cancer, but emergent environmental factors (e.g., diet) could also play a role in its etiopathogenesis.
The aim of this Special Issue is to contribute to the dissemination of basic, translational, or clinical research through high-quality original papers and reviews relating to the epidemiology, etiopathogenesis, prevention, diagnosis, clinical features, prognosis, therapy, and/or management of patients with oral potentially malignant disorders or oral cancer.
Keywords
Oral potentially malignant disorders, Oral lichen planus, Leukoplakia, Erythroplakia, Oral medicine, Oral pathology
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