Guest Editors
Dr. Joanna Szczepanek
E-mail: szczepanekj@umk.pl
Affiliation: Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University, Ul. Wilenska 4, 87-100 Torun, Poland.
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Research Interests: Molecular Biology, Hematology, Cancer Research, Transcriptome, Genome Sequencing, Oncology, Leukemia, Pediatric Hematology, Acute Myeloid Leukemia, Hematological Malignancies, Lymphoma, Pediatric Oncology, Acute Leukemia, Genomics
Summary
The combination of miRNA and CRISPR technologies opens a new chapter in cancer therapy, merging precise gene expression regulation with the capabilities of genome editing. miRNA, with its ability to modulate various molecular processes, and CRISPR, enabling accurate DNA modifications, present unique opportunities for the development of advanced, individualized therapies.
The aim of this special issue is to highlight the potential synergy between these two technologies in improving treatment efficacy, overcoming drug resistance, and creating innovative cancer treatment strategies. We invite submissions that explore the applications of these technologies in both preclinical and clinical settings.
Keywords
Synergy of miRNA and CRISPR; Targeted therapies; Gene therapy; Personalized oncology; Genome editing; Gene expression regulation; Drug resistance