Guest Editors
Hao Peng, Renmin Hospital of Wuhan University, Wuhan, China. E-mail: penghao5868@163.com ; RM000510@whu.edu.cn
María del Mar Requena Mullor, Universidad de Almería, Almeria, Spain. Email: mrm047@ual.es
Wenyi Jin, Renmin Hospital of Wuhan University, Wuhan, China. Email: gin1994@whu.edu.cn
Summary
Metabolic reprogramming is crucial in cancer, altering pathways for growth, adaptation, and immune evasion. It impacts tumor differentiation, biological functions, and leads to cell heterogeneity through epigenetic changes. Shifts like the Warburg effect and adaptations to hypoxia support tumor survival and metastasis, while metabolic changes help evade immune responses. This reprogramming also drives tumor progression, resistance to therapy, and heterogeneity, highlighting the need for targeted therapies.
Potential topics include but are not limited to the following:
1. Mechanisms of Metabolic Reprogramming: Unveiling molecular drivers and pathways in tumor development.
2. Therapeutic Targets: Novel strategies targeting cancer's metabolic vulnerabilities.
3. Metabolic Biomarkers: Identifying biomarkers for diagnosis, prognosis, and treatment response.
4. scRNA-seq in Cancer Metabolism: Exploring tumor metabolic heterogeneity and its implications.
5. Tumor Microenvironment: The role of metabolic reprogramming in tumor-environment interactions.
6. Omics Integration: Combining metabolomics with other omics for holistic cancer metabolism insights.
Keywords
Metabolic Reprogramming, Metabolic Biomarkers, Therapeutic Targets, Cancer Metabolism, Tumor Microenvironment
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