Guest Editors
Prof. Chiara Nicolazzo
Email: chiara.nicolazzo@uniroma1.it
Affiliation: Department of Molecular Medicine, Sapienza Univerist of Rome, Rome, 00161
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Research Interests: clinical pathology, cancer biology, epithelial-mesenchymal transition, immunology
Summary
Over the past decade, liquid biopsies have undoubtedly revolutionized the oncology field, offering ease in tumor sampling, longitudinal monitoring of disease evolution by repeated sampling, determining personalized therapeutic regimens, and screening for drug resistance. However, the liquid biopsy application is not limited only to clinical practice. Indeed, liquid biopsy analysis offers an indirect access to the tumor through all the elements it releases into body fluids. Therefore, the study of analytes, such as circulating tumor cells (CTC), circulating tumor nucleic acids, non-coding DNA, exosomes and circulating proteins allows information on tumor biology and dynamics to be gained through the real-time assessment of the evolving landscape of cancer.
This Special Issue of Oncology Research will cover all the different aspects of liquid biopsy, from technical approaches to ex vitro models, in order to assemble a huge corpus of cancer biology knowledge.
Keywords
circulating tumor cells (CTC), circulating tumor DNA (ctDNA), circulating tumor RNA (ctRNA), non-coding DNA, exosomes, ex vitro study, tumor heterogeneity, technologies, cancer biology, liquid biopsy
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