Open Access
ARTICLE
XINRUI SHI1, XIA GAO1, WENCONG LIU2, XUEJIAO TANG1, JIAYI LIU1, DONGCHEN PAN1, XUEQING DUAN1, YUQING JIN1, WEIYAN REN1, LEI YANG1,*, WENXUAN LIU1,*
Oncology Research, DOI:10.32604/or.2023.028964
（This article belongs to this Special Issue: Role of Reactive Oxygen Species and DNA Damage in Tumor Immunological Responses)
Abstract Hepatocellular carcinoma (HCC) is the most common fatal cancer worldwide, patients with HCC have a high
mortality rate and poor prognosis. PANoptosis is a novel discovery of programmed cell death associated with cancer
development. However, the role of PANoptosis in HCC remains obscure. In this study, we enrolled 274 PANoptosisrelated genes (PANRGs) and screened 8 genes to set up a prognostic model. A previous scoring system calculated
PANscore was utilized to quantify the individual risk level of each HCC patient, and the reliability of the prognostic
model has been validated in an external cohort. Nomogram constructed with PANscore and clinical… More >
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