Open Access
EDITORIAL
V. Rohmer
Oncologie, Vol.21, No.2, pp. 73-73, 2019, DOI:10.3166/onco-2019-0045
Abstract This article has no abstract. More >
Open Access
ARTICLE
R. Coriat
Oncologie, Vol.21, No.2, pp. 75-81, 2019, DOI:10.3166/onco-2019-0046
Abstract Pancreatic neuroendocrine tumours are the
tumours developed at the expense of pancreas and require
a specific diagnostic assessment. The imaging assessment
of a pancreatic neuroendocrine tumour is useful for diagnosis as well as for surgical/medical treatment. Recently, a
number of advances have been made in the field of imaging
pancreatic neuroendocrine tumours, in particular in functional imaging using radiolabelled somatostatin analogues. In
this review, we approach diagnostic progress by focusing on
the advances of recent years. Thus, the interest of conventional imaging (scanner, abdominal ultrasound, and magnetic
resonance imaging), ultrasound endoscopy and the place of
functional imaging mainly with radiolabelled… More >
Open Access
ARTICLE
E. Dansin
Oncologie, Vol.21, No.2, pp. 83-89, 2019, DOI:10.3166/onco-2019-0047
Abstract Typical or atypical bronchial carcinoids are rare
tumors. The management of localized forms is essentially
based on surgery and their prognosis remains good. The
treatment of metastatic forms remains difficult with a low
level of evidence. New treatments are emerging (everolimus,
Lutatherapy), however, their respective place in the therapeutic algorithm should be clarified. Access to expertise
and clinical research via the RENATEN-TENpath network
should be promoted.
Résumé
Les carcinoïdes bronchiques typiques ou atypiques
sont des tumeurs rares. La prise en charge des formes localisées repose essentiellement sur la chirurgie, et leur pronostic
reste bon. Le traitement des formes métastatiques demeure
difficile et… More >
Open Access
ARTICLE
E. Hain, J. Gharios, R. Sindayigaya, S. Gaujoux
Oncologie, Vol.21, No.2, pp. 91-96, 2019, DOI:10.3166/onco-2019-0048
Abstract Neuroendocrine tumors (NET) are rare and can
occur in all parts of the digestive tract. They can be functional or non-functional. All patients presenting NET should be
discussed for the surgical management within the RENATEN tumor board. For sporadic pancreatic NET, surgery is
recommended for non-functional lesion >2 cm in size and/or
associated with ductal dilatation. For non-aggressive tumor,
parenchyma-sparing surgery should be preferred to avoid
exocrine and endocrine pancreatic insufficiency. For small
bowel NET, surgery must always be considered to avoid
complications such as small bowel obstruction. Lymphadenectomy must include at least 8 noded. Surgery must avoid
short bowel… More >
Open Access
ARTICLE
E. Baudin, J. Hadoux, T. de Baere, A. Berdelou, L. Tselikas, C. Caramella, M. Terroir, V. Boige, D. Goere, M. Faron, F. Deschamps, P. Burtin, S. Leboulleux, D. Malka, J.-Y. Scoazec, M. Ducreux
Oncologie, Vol.21, No.2, pp. 97-103, 2019, DOI:10.3166/onco-2019-0049
Abstract This article has no abstract. More >
Open Access
ARTICLE
F. Castinetti, A. Barlier, F. Sebag, D. Taieb
Oncologie, Vol.21, No.2, pp. 105-111, 2019, DOI:10.3166/onco-2019-0050
Abstract Pheochromocytoma and paraganglioma are
tumors leading to increased morbidity and mortality. Over
the last 20 years, several major advances allowed a better
characterization of these tumors, either from an imaging or
from a genetic viewpoint. This is especially the case for the
hereditary characteristics of these tumors, as roughly 20 new
genes have been identified. This is why the initial steps of
the management of a pheochromocytoma and/or a paraganglioma now require a dedicated tertiary referral center.
The aim of this review is to depict the diagnostic steps of
these tumors, so as to allow the clinician to determine the… More >
Open Access
ARTICLE
C. Lepage
Oncologie, Vol.21, No.2, pp. 113-117, 2019, DOI:10.3166/onco-2019-0051
Abstract Little is known about the epidemiology of digestive
neuroendocrine tumours (NETs). NETs remain a rare cancer,
representing 1% of all digestive cancers. In France, incidence
rates are estimated to around 1.1/100,000 inhabitants in males
and 0.9/100,000 in females. The incidence rates got increased
over time, with probably more than 1,000 new cases per year
in France. Because of their relatively good prognosis, NETs
are the second more prevalent digestive cancer after colorectal
cancer. Most digestive NETs are well-differentiated (WDNETs); poorly differentiated neuroendocrine carcinomas
(PDNEC) account for less than 20% of the cases in most of
the series. Among bowel-NETs, the… More >
Open Access
ARTICLE
J.-Y. Scoazec
Oncologie, Vol.21, No.2, pp. 119-124, 2019, DOI:10.3166/onco-2019-0052
Abstract The WHO classification of the tumors of endocrine
organs, published in July 2017 and that of digestive tumors,
released in July 2019, have introduced significant changes in
the classification of gastro-entero-pancreatic neuroendocrine
tumors (NETs), which was unchanged since 2010. The main
change is a new category of well-differentiated neoplasms,
NET G3, in addition to the two previous categories NET G1
and NET G2. The other changes are: 1) the cut-off in Ki-67
index between NET G1 and G2, now set at 3%, 2) the term
used for mixed tumors: MiNEN (mixed neuroendocrine-non
neuroendocrine neoplasm) instead of MANEC (mixed adenoneuroendocrine carcinoma).… More >
Open Access
ARTICLE
E. du Rouchet, C. Dendoncker
Oncologie, Vol.21, No.2, pp. 125-134, 2019, DOI:10.3166/onco-2019-0042
Abstract For a patient suffering from breast cancer, access
to the initial treatment includes several steps like confirmation of an anatomopathological diagnosis, proposition and
establishment of an individualized treatment plan, pretreatment assessments, and access to the technical platform.
The accumulated duration of these intervals plays a role in
the prognosis in the early stages of the disease. In addition, it
is important to manage all the uncertainties, both diagnostic
and prognostic, which will inevitably upset the patient’s psychological balance. Supported by literature, recommendations and more than 20 years of experience in a multidisciplinary centre, the authors propose the organization of an… More >
Login
Register
Submit a Paper
Propose a Special lssue