Open Access

ARTICLE

Differential MMP-2 Activity Induced by Mechanical Compression and Inflammatory Factors in Human Synoviocytes

Yequan Wang^*, Li Yang^*, Jin Zhang^*, Ruyue Xue^*, Zhenyu Tang^*, Wei Huang^†, Dianming Jiang^†, Xinyan Tang^*, Peter Chen^‡, KL Paul Sung^{∗,‡,§,¶}

* “111”project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044, China
† Department of Orthopaedics, Chongqing University of Medical Sciences, Chongqing,China
‡ Departments of Bioengineering, University of California, San Diego, 9500Gilman Drive, La Jolla, CA 92093-0412, USA
§ Department of Orthopaedics,UCSD
¶ Correspondence author. College of Bioengineering, Chongqing University, Chongqing 400044, China. E-mail: klsung@ucsd.edu