Open Access

ARTICLE

Intracellular Calcium Waves in Bone Cell Networks under Single Cell Nanoindentation

X. Edward Guo^∗,†,‡, Erica Takai^∗,‡, Xingyu Jiang^§, Qiaobing Xu^§, George M. Whitesides^§, James T. Yardley^¶, Clark T. Hung^*, Eugene M. Chow^||, Thomas Hantschel^∗∗, Kevin D. Costa^∗

∗ Department of Biomedical Engineering, Columbia University, New York, NY 10027, U.S.A.
† Corresponding Author, E-mail: ed.guo@columbia.edu
‡ These two authors contributed equally to this paper.
§ Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, U.S.A.
¶ Center for Electron Transport in Molecular Nanostructures, Department of Chemical Engineering, Columbia University, New York, NY 10027, U.S.A.
|| Palo Alto Research Center (PARC), 3333 Coyote Hill Road, Palo Alto, CA 94304, U.S.A.
∗∗ Interuniversity Microelectronics Center (IMEC), Kapeldreef 75, B-3001 Leuven, Belgium