Open Access

ARTICLE

An Improved Mathematical Approach for Determination of Molecular Kinetics in Living Cells with FRAP

Tanmay Lele^1,1, Philmo Oh^1,1, Jeffrey A. Nickerson^1,1,2,2, Donald E. Ingber^1,1,3,3

1 Vascular Biology Program, Departments of Pathology and Surgery, Children’s Hospital, Harvard Medical School, Boston, MA 02115-5737
2 Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, North Worcester, MA 01655
3 Donald Ingber, MD, PhDVascular Biology ProgramChildren’s Hospital / Harvard Medical SchoolKarp Family Research Laboratories, Room 11-127
4 00 Longwood Ave.Boston, MA 02115-5737 Ph: 617-919-2223 FAX: 617-730-0230 Email: donald.ingber@childrens.harvard.edu