Open Access

ABSTRACT

Approach to the Flow Rate Distribution of Coronary Branches in the Calculation of Fractional Flow Reserve

by Aike Qiao, Honghui Zhang, Jun Xia

1 College of Life Science and Bioengineering, Beijing University of Technology, China.
* Corresponding Author: Aike Qiao, Email: qak@bjut.edu.cn.

Molecular & Cellular Biomechanics 2019, 16(Suppl.1), 35-35. https://doi.org/10.32604/mcb.2019.05715

Abstract

In order to improve the calculation accuracy of computed tomography angiography-derived fractional flow reserve (FFR_CT), a mathematical model for setting the patient-specific flow boundary condition was proposed, in which some independent physiological parameters, such as myocardial mass, diastolic blood pressure, heart rate and vessel volume were considered. This model was employed to simulate hemodynamics in sixteen patients with coronary stenosis. The results of FFR_CT demonstrated good consistency with invasively measured FFR. The diagnostic accuracy of FFR_CT was 85%. The proposed model offers a new approach to improve the accuracy of FFR_CT, as well as promotes the clinical application of FFR_CT.

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