Open Access

ABSTRACT

Atherosclerotic Plaque Rupture Prediction: Imaging-Based Computational Simulation and Multiphysical Modelling

Zhiyong Li^1,2,*

1 School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.
2 School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology (QUT), Brisbane, QLD, Australia.
* Corresponding author: Zhiyong Li. Email: zylicam@gmail.com.

Molecular & Cellular Biomechanics 2019, 16(Suppl.1), 29-30. https://doi.org/10.32604/mcb.2019.06308

Abstract

In this article, we summarize our previous work in imaging-based computational modelling and simulation of the interaction between blood flow and atherosclerotic plaque. We also discussed our recent developments in multiphysical modelling of plaque progression and destabilization. Significance and translation of the modelling study to clinical practice are discussed in order to better assess plaque vulnerability and accurately predict a possible rupture.

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Keywords

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