Open Access

ARTICLE

Non-Newtonian Blood Flow in Left Coronary Arteries with Varying Stenosis: A Comparative Study

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1 Department of Mechanical Engineering, VNIT, Nagpur, India Pooja Jhunjhunwala- +91-8149884920; pooja.jjw@students.vnit.ac.in
2 Department of Mechanical Engineering, VNIT, Nagpur, India P. M. Padole- +91-9822220713; pmpadole@mec.vnit.ac.in
3 Department of Mechanical Engineering, VNIT, Nagpur, India S.B. Thombre- +91- 9422803441; sbthombre@mec.vnit.ac.in

Molecular & Cellular Biomechanics 2016, 13(1), 1-21. https://doi.org/10.3970/mcb.2016.013.001

Abstract

This paper presents Computational fluid dynamic (CFD) analysis of blood flow in three different 3-D models of left coronary artery (LCA). A comparative study of flow parameters (pressure distribution, velocity distribution and wall shear stress) in each of the models is done for a non-Newtonian (Carreau) as well as the Newtonian nature of blood viscosity over a complete cardiac cycle. The difference between these two types of behavior of blood is studied for both transient and steady states of flow. Additionally, flow parameters are compared for steady and transient boundary conditions considering blood as non-Newtonian fluid. The study shows that the highest wall shear stress (WSS), velocity and pressure are found in artery having stenosis in all the three branches of LCA. The use of Newtonian blood model is a good approximation for steady as well as transient blood flow boundary conditions if shear rate is above 100 s-1. However, the assumption of steady blood flow results in underestimating the values of flow parameters such as wall shear stress, pressure and velocity.

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