Open Access

ARTICLE

Poly (vinyl alcohol)/Graphene Nanocomposite Hydrogel Scaffolds for Control of Cell Adhesion

by Xiaodong Wang, Meng Su, Chuntai Liu, Changyu Shen, Xianhu Liu

1 Department of Materials Science and Engineering, Tongji Zhejiang College, Jiaxing, 314051, China
2 National Engineering Research Center for Advanced Polymer Processing Technology, Zhengzhou University, Zhengzhou, 450002, China

* Corresponding Author: Xianhu Liu. Email:

Journal of Renewable Materials 2020, 8(1), 89-99. https://doi.org/10.32604/jrm.2020.08493

Received 30 August 2019; Accepted 22 October 2019; Issue published 01 January 2020

Abstract

Poly (vinyl alcohol) (PVA)/reduced graphene oxide (rGO) nanocomposites is prepared by the immersion of PVA/graphene oxide (GO) nanocomposites in the reducing agent aqueous solution. The PVA/graphene nanocomposites can be used as scaffold after treatment by chemical crosslinking agents. The surface hydrophilicity of the nanocomposite scaffolds decreased with the addition of GO or rGO by measuring the contact angles of scaffolds. The electrical conductivity of PVA/rGO nanocomposite scaffold increased with rGO content increased. The highest conductivity of PVA/rGO nanocomposite scaffolds with 10 wt% rGO could reach to 12.16 × 10⁻³ S/m. The NIH-3T3 fibroblasts attach and grow well on the surface of PVA/rGO nanocomposite scaffolds with increasing the content of rGO. The number of cells obviously increases on the PVA/rGO nanocomposite scaffolds, especially, at 5 wt% and 10 wt% rGO. Furthermore, a good level of conductivity and a variation in the surface property of the PVA/rGO nanocomposite scaffolds have affected NIH-3T3 fibroblasts grow.

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