Table of Content

Restorative and Regenerative Materials in Biomedical Applications

Submission Deadline: 30 June 2023 Submit to Special Issue

Guest Editors

Shunli Zheng, Associate Professor, College & Hospital of Stomatology, Anhui Medical University, China.
Dr. Shunli Zheng is currently working at College & Hospital of Stomatology, Anhui Medical University (AHMU), China. She obtained her Ph.D. degree at the College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics (NUAA). During her Ph.D. study, she was awarded a visiting scholarship from NUAA to study at Nanyang Technological University (NTU). After obtaining her Ph.D. degree, she joined the School of Materials Science and Engineering at NTU and became a Postdoc Research Fellow from December 2016 to January 2019. Her current research interest mainly focuses on the surface modification of dental restorative resin and the construction of anti-biofouling materials. She is now responsible for 6 items of research projects competitively granted from Natural Science Foundation of China, Natural Science Foundation of Anhui Province, and other institutions. She has published over 40 peer-reviewed articles. According to Google Scholar, these papers have received over 940 citations with an h-index of 14. She is also a reviewer for more than 10 international academic journals and reviewed more than 100 journals papers.

Xiangyang Li, Associate Professor, College & Hospital of Stomatology, Anhui Medical University, China.
Dr. Xiangyang Li received his doctoral degree from Southwest Jiaotong University, China in 2019. Dr. Li is working at College & Hospital of Stomatology, Anhui Medical University as an associate professor now. He is specializing in renewing materials about vascularization and bone regeneration. Special attention is dedicated to nanocoating and multifunction surface fabricating. Dr. Li’s work has been published in more than 20 peer-reviewed top-tier journals and served as a reviewer of several journals.

May Lei Mei, Associate Professor, Faculty of Dentistry, University of Otago, New Zealand.
Prof. May Lei Mei is an associate professor in restorative dentistry, Faculty of Dentistry, University of Otago, New Zealand. Dr. Mei’s research focuses on cariology, in particular, the development of novel bioactive materials for caries management, the effect of silver diamine fluoride on mineralized tissue, collagen, and biofilm.

KC Li, Faculty of Dentistry, University of Otago, New Zealand.
Dr. KC Li is a senior lecturer in biomaterials science at the University of Otago, New Zealand. Dr. Li's research is on the analysis of amorphous and crystalline dental materials, relating their structure, composition, and thermal/mechanical properties to their survivability in clinical use. To replicate such conditions, Dr. Li regularly employs custom models to simulate in vivo conditions and finite element methods to understand and predict the failure of materials.

Summary

Human diseases are often derived from the defect or injury of tissues and organs, which can spread to the lesions of multiple organs, and even lead to the failure of multiple organs. If the tissues and organs can be repaired or regenerated timely, or even replaced in the early stage in the case of individual tissue or organ lesions, the patient's condition can be improved and the progression of the disease could be retarded. In recent years, restorative and regenerative materials based on biomedicine have been widely investigated in basic and clinical research. Such kinds of materials involving resin, implant, scaffold, bioceramic, and hydrogel are committed to promoting repair and regeneration of the body, so as to improve and renew the function of injured tissues and organs; or to construct new tissues and organs to replace the damaged tissues and organs and achieve the reconstruction of normal functions. Accordingly, the physical and chemical properties such as mechanical stability, wear resistance, wettability, and biological performances including biocompatibility, biomechanics, anti-bacteria, mineralization, cell proliferation, osteogenesis, vascularization for these kinds of materials also become the research focuses at present.

 

This Special Issue aims to provide a platform for both research scientists and clinicians in basic and clinical research of restorative and regenerative materials for their potential biomedical applications. It will cover materials processing, characterization, simulation, performance evaluation, and so on. Potential topics include but are not limited to the research areas above. Other sub-topics as long as they align with the general theme of the Special Issue are also encouraged. The original research articles, review articles, and case studies are welcome.



Keywords

restorative and regenerative materials, mechanical stability, biocompatibility, biomechanics, anti-bacteria, mineralization, cell proliferation, osteogenesis, vascularization

Published Papers


  • Open Access

    ARTICLE

    Tensile Properties and Wear Resistance of Mg Alloy Containing High Si as Implant Materials

    Mengqi Cong, Yang Zhang, Yunlong Zhang, Xiao Liu, Yalin Lu, Xiaoping Li
    Journal of Renewable Materials, Vol.11, No.4, pp. 1977-1989, 2023, DOI:10.32604/jrm.2023.023849
    (This article belongs to this Special Issue: Restorative and Regenerative Materials in Biomedical Applications)
    Abstract Magnesium alloy has been considered as one of the third-generation biomaterials for the regeneration and support of functional bone tissue. As a regeneration implant material with great potential applications, in-situ Mg2Si phase reinforced Mg-6Zn cast alloy was comprehensively studied and expected to possess excellent mechanical properties via the refining and modifying of Mg2Si reinforcements. The present study demonstrates that the primary and eutectic Mg2Si phase can be greatly modified by the yttrium (Y) addition. The size of the primary Mg2Si phases can be reduced to ~20 μm with an addition of 0.5 wt.% Y. This phenomenon is mainly attributed to… More >

    Graphic Abstract

    Tensile Properties and Wear Resistance of Mg Alloy Containing High Si as Implant Materials

  • Open Access

    ARTICLE

    Agro-Industrial Waste as a Source of Raw Material: Eggshell and Ash of Agave salmiana Useful for the Synthesis of Hydroxyapatite

    Nora Elizondo-Villarreal, Luz H. Verástegui-Dominguez, Jose J. Quijano-Briones, Francisco J. Vázquez-Rodríguez, Eden Rodríguez-Castellanos, Enrique López-Cuellar, Ernesto Torres-Lopez, Victor M. Castaño-Meneses
    Journal of Renewable Materials, Vol.10, No.12, pp. 3559-3572, 2022, DOI:10.32604/jrm.2022.021945
    (This article belongs to this Special Issue: Restorative and Regenerative Materials in Biomedical Applications)
    Abstract

    Agave salmiana ash and poultry eggshell powder as CaO sources were used for obtaining nanostructured hydroxyapatite (HAP). The synthesis was carried out by the Green Chemistry Hydrothermal Biosynthesis at 180°C with a pH of 5, by reacting CaO from Agave Salmiana ash and Eggshell powder, with dibasic calcium phosphate (CaHPO4•2H2O) in an aqueous solution, with Aloe barbadensis extract. The product was characterized by X-ray diffraction, Fourier-transform infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Transmission Electron Microscopy (TEM). The size and shape of the hydroxyapatite particles changed dramatically in the presence of Aloe barbadensis. Large crystals of Hydroxyapatite were observed… More >

    Graphic Abstract

    Agro-Industrial Waste as a Source of Raw Material: Eggshell and Ash of <i>Agave salmiana</i> Useful for the Synthesis of Hydroxyapatite

  • Open Access

    ARTICLE

    Mechanical Properties, Biocompatibility and Anti-Bacterial Adhesion Property Evaluation of Silicone-Containing Resin Composite with Different Formulae

    Muzi Liao, Hui Tong, Xiangya Huang, Fang Liu, Jingwei He, Sui Mai
    Journal of Renewable Materials, Vol.10, No.12, pp. 3201-3215, 2022, DOI:10.32604/jrm.2022.022090
    (This article belongs to this Special Issue: Restorative and Regenerative Materials in Biomedical Applications)
    Abstract Novel branched silicone methacrylate was developed. The mechanical and biological properties of the resin system were investigated to select the formula proportion with the best overall performance. The novel silicone-containing monomers were combined with an incremental sequence of glass filler concentrations in commonly used Bis-GMA/TEGDMA (50/50, wt./wt.) dental resin systems. Physicochemical properties, surface properties, antibacterial adhesion effect, anti-biofilm effect, protein adsorption, and cytotoxicity were evaluated. The results showed that BSMs did not affect the double bond conversion of dental resin, but could reduce volumetric shrinkage (p < 0.05). The BSM containing resins can resist protein and bacteria adhesion (S. Mutans)… More >

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